撤回：苦参碱在吉西他滨耐药的人胰腺癌细胞中的抗增殖作用是通过线粒体介导的细胞凋亡、抑制细胞迁移、侵袭抑制以及哺乳动物雷帕霉素靶蛋白（mTOR）-TOR/PI3K/AKT 信号通路来介导的。

Retracted: Antiproliferative Effects of Matricine in Gemcitabine-Resistant Human Pancreatic Carcinoma Cells Are Mediated via Mitochondrial-Mediated Apoptosis, Inhibition of Cell Migration, Invasion Suppression, and Mammalian Target of Rapamycin (mTOR)-TOR/PI3K/AKT Signalling Pathway.

机构信息

Department of Emergency Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China (mainland).

Department of Digestive Tumor Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China (mainland).

出版信息

Med Sci Monit. 2021 Mar 25;27:e932342. doi: 10.12659/MSM.932342.

DOI:10.12659/MSM.932342

PMID:33762568

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8009248/

Abstract

An editorial decision has been made to retract this manuscript due to breach of publishing guidelines, following the identification of non-original and manipulated figures. Reference: Kaifeng Fang, Li Wang, LuJia Chen, Tao Liu, Zhi Fang: Antiproliferative Effects of Matricine in Gemcitabine-Resistant Human Pancreatic Carcinoma Cells Are Mediated via Mitochondrial-Mediated Apoptosis, Inhibition of Cell Migration, Invasion Suppression, and Mammalian Target of Rapamycin (mTOR)-TOR/PI3K/AKT Signalling Pathway. Med Sci Monit 2019; 25:2943-2949. 10.12659/MSM.914244.

摘要

由于发现图片非原始且经过处理，因此根据出版准则的规定，本刊做出撤稿决定。参考文献：方开封，王莉，陈露佳，刘涛，方志：苦参碱通过线粒体介导的细胞凋亡、抑制细胞迁移和侵袭、抑制哺乳动物雷帕霉素靶蛋白（mTOR）-TOR/PI3K/AKT 信号通路对吉西他滨耐药人胰腺癌细胞的增殖抑制作用。医学科学监测与促进 2019; 25:2943-2949. 10.12659/MSM.914244.