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术前疼痛敏感度问卷有助于定制关节镜下部分半月板切除术的术后疼痛管理。

Preoperative pain sensitivity questionnaire helps customize pain management after arthroscopic partial meniscectomy.

机构信息

Arthroscopy and Sports Injuries Unit, Rabin Medical Center, Hasharon Hospital, 7 Keren Kayemet St, 49372, Petach-Tikva, Israel.

Orthopedic Department, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv-Yafo, Israel.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2021 Dec;29(12):4198-4204. doi: 10.1007/s00167-021-06438-6. Epub 2021 Mar 11.

Abstract

PURPOSE

To evaluate correlations between preoperative pain sensitivity and postoperative analgesic consumption together with pain perception shortly after arthroscopic partial meniscectomy in non-arthritic knees.

METHODS

Ninety-nine patients who underwent primary arthroscopic meniscectomy were prospectively divided into three postoperative treatment groups that were prescribed with betamethasone injection (at the end of surgery), oral celecoxib or rescue analgesia (control). Preoperative pain sensitivity was evaluated by pain sensitivity questionnaires (PSQ). Patients were followed for the first three postoperative weeks to evaluate knee injury and osteoarthritis outcome score (KOOS) pain scores and analgesics consumption. Statistical analysis included correlations among preoperative pain sensitivity, postoperative pain levels and analgesics consumption. A receiver operating characteristic curve was plotted to investigate the cutoff values of the PSQ score to predict insufficient postoperative pain reduction.

RESULTS

There were no differences at baseline among all study groups in age, sex, BMI, level of activity, comorbidities and surgical findings. At the final follow-up, KOOS pain scores improved in all groups (p < 0.001). Mean final KOOS pain scores were 76.1 ± 15.2 for the betamethasone group, 70.8 ± 12.6 for the celecoxib group and 78.7 ± 11.6 for the control group. No differences in scores were observed among groups (n.s.). In the control group, a negative correlation was observed between PSQ score and KOOS-pain scores at the end of the follow-up in addition to a positive correlation between PSQ score and rescue analgesia consumption at the first postoperative week. The optimal cutoff value for PSQ score to predict insufficient improvement in KOOS-pain subscale was 5.0 points.

CONCLUSIONS

A cutoff value of pain sensitivity questionnaire score above 5.0 points was determined to identify patients with higher sensitivity to pain who underwent arthroscopic partial meniscectomy. These patients reported relatively increased pain and consumed more rescue analgesics postoperatively unless treated with a single intraoperative corticosteroids injection or oral non-steroidal anti-inflammatories. Therefore, surgeons can use pain sensitivity questionnaire score as a preoperative tool to identify patients with high sensitivity to pain and customize their postoperative analgesics protocol to better fit their pain levels.

LEVEL OF EVIDENCE

II.

摘要

目的

评估非关节炎膝关节关节镜部分半月板切除术后早期的术前疼痛敏感性与术后镇痛药物消耗及疼痛感知之间的相关性。

方法

前瞻性地将 99 例接受初次关节镜半月板切除术的患者分为三组术后治疗组,即关节内注射倍他米松(手术结束时)、口服塞来昔布或解救性镇痛(对照组)。术前疼痛敏感性通过疼痛敏感性问卷(PSQ)进行评估。患者在术后前 3 周进行随访,以评估膝关节损伤和骨关节炎结局评分(KOOS)疼痛评分和镇痛药消耗。统计分析包括术前疼痛敏感性、术后疼痛水平和镇痛药消耗之间的相关性。绘制受试者工作特征曲线以研究 PSQ 评分的截断值来预测术后疼痛缓解不足。

结果

在基线时,所有研究组在年龄、性别、BMI、活动水平、合并症和手术发现方面均无差异。在最终随访时,所有组的 KOOS 疼痛评分均有所改善(p<0.001)。倍他米松组的平均最终 KOOS 疼痛评分为 76.1±15.2,塞来昔布组为 70.8±12.6,对照组为 78.7±11.6。组间评分无差异(n.s.)。在对照组中,除了在术后第 1 周时 PSQ 评分与解救性镇痛药物消耗呈正相关外,PSQ 评分与随访结束时的 KOOS 疼痛评分之间也呈负相关。PSQ 评分预测 KOOS 疼痛亚量表改善不足的最佳截断值为 5.0 分。

结论

确定 PSQ 评分的截断值高于 5.0 分,以识别接受关节镜部分半月板切除术的疼痛敏感性较高的患者。这些患者术后报告疼痛相对增加,且需要更多的解救性镇痛药物,除非接受单次关节内皮质类固醇注射或口服非甾体抗炎药治疗。因此,外科医生可以使用疼痛敏感性问卷评分作为术前工具,识别对疼痛敏感的患者,并根据其疼痛水平定制术后镇痛方案。

证据水平

II 级。

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