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巴西本土传播的东/中/南非基因型基孔肯雅病毒。

Autochthonous Transmission of East/Central/South African Genotype Chikungunya Virus, Brazil.

出版信息

Emerg Infect Dis. 2017 Oct;23(10):1737-1739. doi: 10.3201/eid2310.161855.

DOI:10.3201/eid2310.161855
PMID:28930027
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5621531/
Abstract

We isolated East/Central/South African genotype chikungunya virus during the 2016 epidemic in Rio de Janeiro, Brazil. Genome sequencing revealed unique mutations in the nonstructural protein 4 (NSP4-A481D) and envelope protein 1 (E1-K211T). Moreover, all Brazil East/Central/South isolates shared the exclusive mutations E1-M407L and E2-A103T.

摘要

我们在 2016 年巴西里约热内卢的疫情期间分离到了东/中/南非基因型基孔肯雅病毒。基因组测序显示非结构蛋白 4（NSP4-A481D）和包膜蛋白 1（E1-K211T）存在独特突变。此外，所有巴西东/中/南分离株都共享独特的 E1-M407L 和 E2-A103T 突变。

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