大逃亡？逃避中和反应的 SARS-CoV-2 变体。
The great escape? SARS-CoV-2 variants evading neutralizing responses.
机构信息
Centre de Recherche du CHUM, Montreal, QC H2X 0A9, Canada; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC H2X 0A9, Canada.
Centre de Recherche du CHUM, Montreal, QC H2X 0A9, Canada; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC H2X 0A9, Canada; Department of Microbiology and Immunology, McGill University, Montreal, QC H3A 2B4, Canada.
出版信息
Cell Host Microbe. 2021 Mar 10;29(3):322-324. doi: 10.1016/j.chom.2021.02.010.
In the latest issues of Cell Host & Microbe and Cell, three articles describe new mutations in the SARS-CoV-2 Spike receptor binding domain that escape neutralizing responses. These highlight the importance of surveillance of SARS-CoV-2 evolution to anticipate and manage new variants that could impact reinfection, vaccine efficacy, and immunotherapies.
在最新一期的《Cell Host & Microbe》和《Cell》杂志上，有三篇文章描述了新冠病毒刺突受体结合域中的新突变，这些突变能够逃避中和反应。这些发现强调了监测新冠病毒进化以预测和管理可能影响再次感染、疫苗效力和免疫疗法的新变种的重要性。
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