Marshall V C, Ross H, Scott D F, McInnes S, Thomson N, Atkins R C, Mathew T H, Kincaid-Smith P S
Med J Aust. 1977 Sep 10;2(11):353-6.
Preservation of cadaveric renal allografts by ice storage and by machine perfusion after a preliminary flush with a hypertonic citrate solution has been compared in a prospective clinical trial between matched pairs of kidneys from the same cadaver donor. Over a two-year period, ice storage after flushing with the new solution gave results comparable with machine perfusion. Times of warm ischaemia and total times of storage were similar in ice-stored and machine-perfused kidneys and averaged about 16 hours. In each group of recipients, more than half of the kidneys had good early function and one-year survival times were also similar.
在一项前瞻性临床试验中,对来自同一尸体供体的配对肾脏进行了比较,研究了用高渗柠檬酸盐溶液初步冲洗后,通过冰储存和机器灌注来保存尸体肾移植器官的效果。在两年的时间里,用新溶液冲洗后进行冰储存的结果与机器灌注相当。冰储存和机器灌注的肾脏的热缺血时间和总储存时间相似,平均约为16小时。在每组接受者中,超过一半的肾脏早期功能良好,一年生存率也相似。