Department of Surgery, Pediatric Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Department of Surgery, Baylor College of Medicine, 6701 Fannin Street, Houston, TX 77030, USA.
Surg Oncol Clin N Am. 2021 Apr;30(2):291-304. doi: 10.1016/j.soc.2020.11.010. Epub 2021 Feb 10.
Surgeons caring for patients with neuroblastoma must be familiar with recent developments in assessing risk. In particular, the Children's Oncology Group, along with major international groups, uses the International Neuroblastoma Risk Group Staging System as a risk assessment tool. Accurate risk determination is essential for optimal surgical therapy. Some tumors like neonatal adrenal neuroblastomas and those in the metastatic category can be observed. Very-low-risk and low-risk neuroblastomas can be treated with surgery alone. Intermediate-risk tumors also often require systemic chemotherapy.
外科医生在照顾神经母细胞瘤患者时，必须熟悉风险评估的最新进展。特别是，儿童肿瘤学组与主要的国际组织一起，将国际神经母细胞瘤风险组分期系统用作风险评估工具。准确的风险确定对于最佳手术治疗至关重要。一些肿瘤，如新生儿肾上腺神经母细胞瘤和转移性肿瘤，可以进行观察。极低风险和低风险的神经母细胞瘤可以单独通过手术治疗。中危肿瘤通常也需要全身化疗。
