EXCEL试验：介入医生的观点。
The EXCEL Trial: The Interventionalists' Perspective.
作者信息
Hunter George William, Sharma Vinoda, Varma Chetan, Connolly Derek
机构信息
Department of Cardiology, Sandwell and West Birmingham Hospitals NHS Trust Birmingham, UK.
出版信息
Eur Cardiol. 2021 Mar 2;16:e01. doi: 10.15420/ecr.2020.32. eCollection 2021 Feb.
Abstract
Left main stem (LMS) disease is identified in up to 5% of diagnostic angiography cases, and is associated with significant morbidity and mortality due to the proportion of myocardium it subtends. In the past 10 years, there has been a significant change in the way we contemplate treating lesions in the LMS due to evolving experience and evidence in percutaneous coronary intervention (PCI) strategies and technologies. This has been reflected in recent changes in European and International guidance on managing patients with this lesion subset. Here, the authors provide an overview of the current literature regarding the management of LMS disease using PCI in light of new developments and emerging concepts in this field, specifically looking at the recent EXCEL trial.
摘要
左主干（LMS）病变在高达5%的诊断性血管造影病例中被发现，由于其所覆盖的心肌比例，与显著的发病率和死亡率相关。在过去十年中，由于经皮冠状动脉介入治疗（PCI）策略和技术方面不断积累的经验和证据，我们对LMS病变治疗方式的思考发生了重大变化。这一点已反映在欧洲和国际上关于这类病变亚组患者管理的最新指南变化中。在此，作者根据该领域的新进展和新出现的概念，特别是近期的EXCEL试验，概述了有关使用PCI治疗LMS病变的当前文献。
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