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评估撒哈拉以南非洲地区 0-59 月龄儿童严重急性营养不良并发症的治疗指南、实践和结局:SAMAC 研究方案。

Evaluation of the treatment guidelines, practices and outcomes of complicated severe acute malnutrition in children aged 0-59 months in sub-Saharan Africa: a study protocol for the SAMAC study.

机构信息

Centre of Excellence for Nutrition, North-West University, Potchefstroom, South Africa.

Pediatric Epidemiology, Department of Pediatrics, Medical Faculty, Leipzig University, Leipzig, Germany.

出版信息

Pan Afr Med J. 2020 Aug 4;36:241. doi: 10.11604/pamj.2020.36.241.19584. eCollection 2020.

Abstract

INTRODUCTION

in hospitals across Africa, the case fatality rates of severe acute malnutrition (SAM) have remained consistently high (over 20%), despite the existence of the WHO treatment guideline. This has been attributed to inconsistencies in the implementation of the WHO treatment guidelines in sub-Saharan African countries. In spite of this awareness, the SAM treatment guidelines adopted by various sub-Saharan African countries and hospitals are unknown. Knowledge of the exact treatment practices employed in the management of SAM in different hospitals in sub-Saharan Africa is not known. This study aims to investigate the admission criteria, in-patient treatment guidelines and practices and outcomes of complicated SAM in sub-Saharan African children aged 0-59 months.

METHODS

this is an observational study which involves the extraction of admission, treatment and discharge data from the medical records of infants and children aged 0-59 months diagnosed and treated for complicated SAM in sub-Saharan Africa. This information is being used to develop a comprehensive database on the treatment of complicated SAM across sub-Saharan Africa. Information on the national and hospital guidelines for the treatment of complicated SAM is also collected.

RESULTS

results of this study will serve as a useful resource on the true reflection of the treatment of complicated SAM across sub-Saharan Africa and will provide valuable information for optimising SAM treatment.

CONCLUSION

in order to advocate best practice and reduce SAM-related mortality in sub-Saharan Africa, the identification of the different diagnostic and treatment methods and respective outcomes across different hospitals and countries is imperative.

摘要

简介

在非洲各地的医院中,严重急性营养不良(SAM)的病死率一直居高不下(超过 20%),尽管有世界卫生组织的治疗指南。这归因于撒哈拉以南非洲国家在执行世界卫生组织治疗指南方面存在不一致性。尽管有这种认识,但各国和各医院采用的 SAM 治疗指南仍不清楚。对于撒哈拉以南非洲不同医院管理 SAM 中使用的确切治疗方法也不得而知。本研究旨在调查撒哈拉以南非洲 0-59 个月儿童中严重急性营养不良的入院标准、住院治疗指南和实践以及治疗结果。

方法

这是一项观察性研究,从撒哈拉以南非洲诊断和治疗严重急性营养不良的 0-59 个月婴儿和儿童的病历中提取入院、治疗和出院数据。该信息用于开发撒哈拉以南非洲复杂严重急性营养不良治疗的综合数据库。还收集了有关治疗复杂严重急性营养不良的国家和医院指南的信息。

结果

该研究的结果将成为反映撒哈拉以南非洲治疗复杂严重急性营养不良的真实情况的有用资源,并为优化严重急性营养不良的治疗提供有价值的信息。

结论

为了倡导最佳实践并降低撒哈拉以南非洲的 SAM 相关死亡率,必须确定不同医院和国家之间不同的诊断和治疗方法以及各自的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb1/7908334/d736db114cfd/PAMJ-36-241-g001.jpg

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