Rupawala Taher Abbas, Patel Shital Mayank, Shah Naiya Hitesh, Sanghvi Kunj Bhupeshchandra, Makwana Sanjay Vinubhai, Bhimani Kruna Kantilal
Department of Oral and Maxillofacial Surgery, Ahmedabad Municipal Corporation Dental College and Hospital, Ahmedabad, Gujarat, India.
N.Y.U College of Dentistry, New York University, New York, USA.
Ann Maxillofac Surg. 2020 Jul-Dec;10(2):335-343. doi: 10.4103/ams.ams_40_20. Epub 2020 Dec 23.
Recently, initiation and enhancement of extraction socket healing has been amplified by platelet concentrates, whereas the positive role of Sticky bone has been focused on maintaining alveolar bone dimensions. This study aimed to determine the effectiveness of Sticky Bone for socket grafting of mandibular third molars (M3Ms) in terms of soft- and hard-tissue healing.
This split-mouth prospective trial constituted prophylactic removal of M3Ms with Sticky bone grafted in the study site as a primary predictor variable. Patients underwent 3 months of mandatory follow-up where pain, swelling, interincisal mouth opening, and gingival healing were measured on the 3, 7, and 14 day using the Numeric Rating Scale, anatomic landmarks, steel metric ruler, and criteria given by Landry . respectively. Radiological healing was calculated based on the height of the socket, Kelly's Index, and histogram values immediately after the procedure at 1 week, 1 month, and 3 months, respectively. Statistical comparison was made using Paired -test. < 0.05 was considered significant.
Forty-seven patients (mean 26.83 ± 6.58 years) demonstrated significantly lesser pain, swelling, and better gingival healing at the study site on multiple periods of follow-up. Rapid bone formation with superior density, lesser alveolar resorption, earlier bone blending, and trabecular formation were noticed on the study site with a significant difference at all time intervals.
Sticky bone was chosen as the graft owing to advantages such as simple preparation, convenient handling characteristics, safety, evident postoperative patient comfort, better retention of the clot, enhanced soft-tissue healing, absence of infection, and decreased osseous deformation as compared to the control site. This study validated the role of Sticky bone as an indispensable component of regenerative therapy in the orofacial osseous tissues as it was an ideal biologic graft with fibrin rich structure.
This study validated the role of Sticky bone as an indispensable component of regenerative therapy in the orofacial osseous tissues as it was an ideal biologic graft with fibrin rich structure.
最近，血小板浓缩物促进了拔牙窝愈合的启动和增强，而粘性骨的积极作用则集中在维持牙槽骨尺寸方面。本研究旨在确定粘性骨在下颌第三磨牙（M3M）拔牙窝植骨中对软组织和硬组织愈合的有效性。
本双盲前瞻性试验将在研究部位植入粘性骨预防性拔除M3M作为主要预测变量。患者接受3个月的强制随访，分别在第3、7和14天使用数字评分量表、解剖标志、钢尺以及兰德里给出的标准测量疼痛、肿胀、切牙间开口度和牙龈愈合情况。分别在术后即刻、1周、1个月和3个月根据拔牙窝高度、凯利指数和直方图值计算放射学愈合情况。采用配对t检验进行统计学比较。P<0.05被认为具有显著性。
47例患者（平均年龄26.83±6.58岁）在多个随访期内研究部位的疼痛、肿胀明显减轻，牙龈愈合更好。研究部位出现了密度更高的快速骨形成、牙槽骨吸收减少、骨融合更早和小梁形成，在所有时间间隔均有显著差异。
选择粘性骨作为移植材料是因为其具有制备简单、操作方便、安全、术后患者舒适度明显、血凝块保留更好、软组织愈合增强、无感染以及与对照部位相比骨变形减少等优点。本研究验证了粘性骨作为口腔颌面骨组织再生治疗不可或缺的组成部分的作用，因为它是一种具有富含纤维蛋白结构的理想生物移植物。
本研究验证了粘性骨作为口腔颌面骨组织再生治疗不可或缺的组成部分的作用，因为它是一种具有富含纤维蛋白结构的理想生物移植物。
