Department of Oral Pathology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University, School of Medicine, Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology, Shanghai, People's Republic of China.
Int J Oral Maxillofac Surg. 2010 Mar;39(3):235-42. doi: 10.1016/j.ijom.2009.10.016. Epub 2009 Nov 29.
There is little information in the English-language literature about the epidemiology of salivary gland neoplasms in the eastern Chinese population. A large retrospective study (6982 primary salivary tumors during 23 years) was carried out to investigate the clinicopathological features (tumor location, patient sex and age) of these tumors in this population. 3593 tumors were in males and 3389 in females. Pleomorphic adenoma (69%) was the most common tumor and 20% were located in minor glands. 92% of Warthin's tumors occurred in males. Malignant tumors were predominantly adenoid cystic carcinoma (30%) and mucoepidermoid carcinoma (30%). Incidences of lymphoepithelial carcinomas (5%) and polymorphous low-grade adenocarcinoma (1%) of malignant tumors were identified. 28% of tumors originated from minor glands. Most findings were similar to those in the literature, with some variations. The salivary tumors slightly predominated in males. Relatively higher incidences of minor gland tumors and specifically of pleomorphic adenoma in minor glands were noted. Adenoid cystic carcinoma and mucoepidermoid carcinoma constituted the most common malignancies. There was a high incidence of lymphoepithelial carcinomas but a low incidence of polymorphous low-grade adenocarcinoma. The historical significant male predominance of Warthin's tumor was confirmed.
中文文献中关于中国东部人群涎腺肿瘤的流行病学资料很少。我们进行了一项大型回顾性研究（23 年间共 6982 例原发性涎腺肿瘤），以调查该人群中这些肿瘤的临床病理特征（肿瘤位置、患者性别和年龄）。3593 例发生于男性，3389 例发生于女性。多形性腺瘤（69%）最常见，20%位于小涎腺。92%的沃辛瘤发生于男性。恶性肿瘤主要为腺样囊性癌（30%）和黏液表皮样癌（30%）。淋巴上皮癌（5%）和多形性低度恶性腺癌（1%）的发病率也有所确定。28%的肿瘤来源于小涎腺。大多数发现与文献中的相似，但也存在一些差异。涎腺肿瘤在男性中略占优势。小涎腺肿瘤和特别是小涎腺多形性腺瘤的相对发病率较高。腺样囊性癌和黏液表皮样癌构成最常见的恶性肿瘤。淋巴上皮癌的发病率较高，但多形性低度恶性腺癌的发病率较低。沃辛瘤的历史显著的男性优势得到了证实。
