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Frontline treatment with the combination obinutuzumab ± chlorambucil for chronic lymphocytic leukemia outside clinical trials: Results of a multinational, multicenter study by ERIC and the Israeli CLL study group.在临床试验之外，采用奥滨尤妥珠单抗联合苯丁酸氮芥进行慢性淋巴细胞白血病的一线治疗：ERIC 和以色列 CLL 研究组的一项多中心跨国研究结果。
Am J Hematol. 2020 Jun;95(6):604-611. doi: 10.1002/ajh.25766. Epub 2020 Mar 14.
2
iwCLL guidelines for diagnosis, indications for treatment, response assessment, and supportive management of CLL.iwCLL 指南：用于 CLL 的诊断、治疗指征、疗效评估和支持性管理。
Blood. 2018 Jun 21;131(25):2745-2760. doi: 10.1182/blood-2017-09-806398. Epub 2018 Mar 14.
3
Real-world Data for Clinical Evidence Generation in Oncology.真实世界数据在肿瘤学临床证据生成中的应用。
J Natl Cancer Inst. 2017 Nov 1;109(11). doi: 10.1093/jnci/djx187.
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Clinical Data Reuse or Secondary Use: Current Status and Potential Future Progress.临床数据的再利用或二次使用：现状与未来潜在进展
Yearb Med Inform. 2017 Aug;26(1):38-52. doi: 10.15265/IY-2017-007. Epub 2017 Sep 11.
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The Effect of the General Data Protection Regulation on Medical Research.《通用数据保护条例》对医学研究的影响
J Med Internet Res. 2017 Feb 24;19(2):e47. doi: 10.2196/jmir.7108.
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Chronic lymphocytic leukaemia.慢性淋巴细胞白血病
Nat Rev Dis Primers. 2017 Feb 9;3:17008. doi: 10.1038/nrdp.2017.8.
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Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study.定型B细胞受体免疫球蛋白在慢性淋巴细胞白血病中的临床疗效：一项回顾性多中心研究
Lancet Haematol. 2014 Nov;1(2):e74-84. doi: 10.1016/S2352-3026(14)00005-2. Epub 2014 Nov 3.
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The FAIR Guiding Principles for scientific data management and stewardship.科学数据管理和保存的 FAIR 指导原则。
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Recurrent mutations refine prognosis in chronic lymphocytic leukemia.反复出现的突变可改善慢性淋巴细胞白血病的预后。
Leukemia. 2015 Feb;29(2):329-36. doi: 10.1038/leu.2014.196. Epub 2014 Jun 19.
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Challenges and Solutions for Collecting and Analyzing Real World Data: The Eric CLL Database as an Illustrative Example.

作者信息

Chatzidimitriou Anastasia, Minga Eva, Chatzikonstantinou Thomas, Moreno Carol, Stamatopoulos Kostas, Ghia Paolo

机构信息

Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.

Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

出版信息

Hemasphere. 2020 Sep 30;4(5):e425. doi: 10.1097/HS9.0000000000000425. eCollection 2020 Oct.

DOI:10.1097/HS9.0000000000000425
PMID:33709059
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7934894/
Abstract
摘要