Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Yamadaoka 2-1, Suita, Osaka 565-0871, Japan.
J Am Chem Soc. 2021 Mar 24;143(11):4112-4118. doi: 10.1021/jacs.1c00228. Epub 2021 Mar 12.
The stereospecific, substrate (nitrogen source)-controlled intermolecular - and -1,2-diaminations of unactivated alkenes using the same catalysis (an iodine catalyst) is reported. The combined use of the two potential methods provides access to all of the disastereomeric forms of 1,2-diamines in spite of the availability of - and -alkenes, and the resulting products can be readily converted into free vicinal diamines.
本文报道了使用相同的催化体系（碘催化剂），立体专一、底物（氮源）控制的非活化烯烃的分子间-和-1,2-二胺化反应。尽管存在顺式和反式烯烃，但这两种潜在方法的结合使用为所有的 1,2-二胺非对映异构体形式提供了途径，并且得到的产物可以很容易地转化为游离的偕二胺。
