Stolk P W, Firth E C
Department of General and Large Animal Surgery, State University, Utrecht, The Netherlands.
Cornell Vet. 1988 Apr;78(2):191-206.
Intra-osseous pressure was measured in the third metatarsal bone of 8 pony foals at the age of 1, 3, 6 and 26 weeks of age, and on one occasion in the third metatarsal bone of 5 ponies aged 1-5 years; the animals were under general anesthesia and in lateral recumbency. Saphenous venous pressure and lateral superficial plantar metatarsal arterial pressure were also monitored throughout the procedure. There were no statistically significant changes in the epiphyseal, diaphyseal, venous or arterial pressures with increasing age of the foals. There was no statistically significant difference between the mean epiphyseal and mean diaphyseal pressures in the foals. Individually however, the diaphyseal pressure exceeded the epiphyseal pressure in 32 of the 36 measurements made in the foals. Saphenous vein occlusion and intravenous adrenalin administration showed that both venous and arterial pressures influence intra-osseous pressure. Intra-osseous injection of heparinized saline on one side of the growth plate produced an immediate massive increase in intra-osseous pressure on that side of the growth plate, but in almost all cases a concomitant rise in intraosseous pressure on the other side of the physis did not occur. Simulated effusion of the metatarsophalangeal joint was associated with an increase in intraosseous pressure in the adjacent metatarsal epiphysis, and flexion of the joint with an increase in intraosseous pressure in both the epiphysis and the metaphysis.
在8匹1周龄、3周龄、6周龄和26周龄的小马驹的第三跖骨中测量骨内压，并在1次测量中对5匹1至5岁小马的第三跖骨进行测量；动物处于全身麻醉和侧卧状态。在整个过程中还监测了隐静脉压和外侧足底跖骨动脉压。随着马驹年龄的增长，骨骺、骨干、静脉或动脉压没有统计学上的显著变化。马驹的平均骨骺压和平均骨干压之间没有统计学上的显著差异。然而，单独来看，在对马驹进行的36次测量中，有32次骨干压超过了骨骺压。隐静脉闭塞和静脉注射肾上腺素表明，静脉压和动脉压都会影响骨内压。在生长板一侧注射肝素化盐水会立即导致该侧生长板骨内压大幅升高，但在几乎所有情况下，骨骺另一侧的骨内压并未随之升高。模拟跖趾关节积液与相邻跖骨骨骺骨内压升高有关，关节屈曲则与骨骺和干骺端骨内压升高有关。
