Obermayer-Pietsch Barbara, Fössl Ines, Dimai Hans Peter
Klin. Abteilung Endokrinologie und Diabetologie, Univ. Klinik für Innere Medizin, Medizinische Universität Graz, Auenbruggerplatz 15, 8036, Graz, Österreich.
Internist (Berl). 2021 May;62(5):474-485. doi: 10.1007/s00108-021-00993-3. Epub 2021 Mar 12.
The need for a long-term pharmacological treatment of osteoporosis, the problem of potential compliance issues and also potentially severe side effects during the treatment are of central interest not only for patients but also for medical guidelines and prescribers. This review summarizes the current knowledge about the pharmacological substances used and the current scientifically based guidelines and approaches for the long-term use as well as the monitoring and potential treatment changes with a special focus on future developments.
骨质疏松症长期药物治疗的必要性、潜在的依从性问题以及治疗期间可能出现的严重副作用,不仅是患者关注的核心问题,也是医学指南制定者和开处方者关注的核心问题。本综述总结了目前关于所用药物物质的知识,以及当前基于科学的长期使用指南和方法,以及监测和潜在的治疗调整,并特别关注未来的发展。