Wessex Cardiothoracic Centre, Southampton General Hospital, Southampton, UK.
Department of Microbiology, Southampton General Hospital, Southampton, UK.
Echocardiography. 2021 Apr;38(4):697-700. doi: 10.1111/echo.15007. Epub 2021 Mar 12.
Tropheryma whipplei is a bacterium that causes a rare infection called Whipple's disease and can cause devastating effects if left untreated. It is important to recognize that patients with this infection may present with atypical symptoms and are often apyrexial with normal inflammatory markers. Moreover, routine blood cultures often do not isolate these bacteria in conventional growth media. Therefore, it requires a high level of clinical suspicion to make this diagnosis. Here, we present two cases of Tropheryma whipplei aortic valve endocarditis, with atypical presentation and similar unusual but striking echocardiographic images.
热带口炎性腹泻相关物质是一种可引起罕见感染——热带口炎性腹泻的细菌，如果不加以治疗，可能会产生严重的后果。需要注意的是，患有这种感染的患者可能会出现非典型症状，并且通常没有发热，炎症标志物也正常。此外，常规血培养通常无法在常规生长培养基中分离出这些细菌。因此，需要高度的临床怀疑才能做出这种诊断。在这里，我们介绍了两例热带口炎性腹泻相关物质主动脉瓣心内膜炎的病例，这些病例表现不典型，且超声心动图图像也类似，较为罕见但具有特征性。
