Polio J, Leonard R, Groszmann R J, Vogel G
Hepatic Hemodynamic Laboratory, Veterans Administration Medical Center, West Haven, Connecticut 06516.
Dig Dis Sci. 1988 Jun;33(6):737-40. doi: 10.1007/BF01540439.
A new small noninvasive pressure-sensitive capsule for the endoscopic measurement of esophageal varix pressure was evaluated and compared to an initial Yale-designed capsule to test the hypothesis that the diameter of the capsule measuring surface is a limiting factor for the accuracy and variability of capsule pressure measurements. Capsule pressures obtained with each capsule, using rabbit mesenteric vessels comparable in size to human esophageal varices, were correlated with direct intraluminal pressure measurements. There was an excellent correlation between capsule pressure measurements obtained with the small capsule and intraluminal pressure (r2 = 0.97) which was significantly greater than the correlation obtained when the initial capsule was studied (r2 = 0.89, P less than 0.01). The variability of capsule pressure measurements obtained with the small capsule was less than that observed when measurements were obtained with the initial capsule (P less than 0.01). Therefore, this new small capsule should provide the most accurate and reproducible noninvasive measurements of variceal pressure.
一种用于内镜测量食管静脉曲张压力的新型小型无创压敏胶囊进行了评估，并与最初耶鲁设计的胶囊进行比较，以检验以下假设：胶囊测量表面的直径是胶囊压力测量准确性和变异性的限制因素。使用与人类食管静脉曲张大小相当的兔肠系膜血管，通过每个胶囊获得的胶囊压力与直接腔内压力测量值相关。小型胶囊获得的胶囊压力测量值与腔内压力之间存在极好的相关性（r2 = 0.97），这显著大于研究最初胶囊时获得的相关性（r2 = 0.89，P小于0.01）。小型胶囊获得的胶囊压力测量值的变异性小于使用最初胶囊进行测量时观察到的变异性（P小于0.01）。因此，这种新型小型胶囊应能提供最准确和可重复的静脉曲张压力无创测量。
