Karhunen U
Department of Ophthalmology, Helsinki University Central Hospital, Finland.
Dev Pharmacol Ther. 1988;11(2):92-5. doi: 10.1159/000457672.
Methohexitone (10 mg/kg) was administered before 464 general anaesthesias for 317 children following intramuscular atropine and pethidine for various ophthalmological procedures. Approximately 70% of the children were asleep when anaesthesia was continued or started, usually with halothane in nitrous oxide and oxygen. Although the dose of methohexitone used here was smaller than that recommended in the literature, the results of the study did not greatly differ from earlier investigations in which no other premedication was given but where 20 mg/kg methohexitone was used.
在为317名儿童进行464次全身麻醉以实施各种眼科手术前，先给予肌肉注射阿托品和哌替啶，然后给予甲己炔巴比妥（10毫克/千克）。当继续麻醉或开始麻醉时，约70%的儿童已入睡，麻醉通常采用氟烷与一氧化二氮和氧气混合使用。尽管此处使用的甲己炔巴比妥剂量低于文献推荐剂量，但该研究结果与早期研究并无太大差异，早期研究未给予其他术前用药，但使用的甲己炔巴比妥剂量为20毫克/千克。
