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低渗口服补液盐溶液(LORS)在儿童脱水管理中的应用。

Low Osmolarity Oral Rehydration Salt Solution (LORS) in Management of Dehydration in Children.

机构信息

Department of Pediatrics, MGM Institute of Health Sciences, Navi Mumbai, Maharashtra, India. Correspondence to: Prof. Nimain Mohanty, Department of Paediatrics, MGM Medical College, Kamothe, Navi Mumbai 410209, Maharashtra, India.

Department of Gastroenterology, Liver and Nutrition, PGIMER, Chandigarh, India.

出版信息

Indian Pediatr. 2021 Mar 15;58(3):266-272. doi: 10.1007/s13312-021-2168-8.

Abstract

JUSTIFICATION

The IAP last published the guidelines "Comprehensive Management of Diarrhea" in 2006 and a review in 2016. The WHO in 2002 and the Government of India in 2004 recommended low osmolarity rehydration solution (LORS) as the universal rehydration solution for all ages and all forms of dehydration. However, the use of LORS in India continues to be unacceptably low at 51%, although awareness about ORS has increased from a mere 14% in 2005 to 69% in 2015. Availability of different compositions of ORS and brands in market added to the confusion.

PROCESS

The Indian Academy of Pediatrics constituted a panel of experts from the fields of pediatrics, pediatric gastroenterology and nutrition to update on management of dehydration in children with particular reference to LORS and issue a current practice guideline. The committee met twice at CIAP HQ to review all published literature on the aspect. Brief presentations were made, followed by discussions. The draft paper was circulated by email. All relevant inputs and suggestions were incorporated to arrive at a consensus on this practice guideline.

OBJECTIVES

To summarize latest literature on ORT and empower pediatricians, particularly those practicing in rural areas, on management of dehydration by augmenting LORS use.

RECOMMENDATIONS

It was stressed that advantages of LORS far out-weigh its limitations. Increased use of LORS can only be achieved by promoting better awareness among public and health-care providers across all systems of medicine. LORS can also be useful in managing dehydration in non-diarrheal illness. More research is required to modify ORS further to make it safe and effective in neonates, severe acute malnutrition, renal failure, cardiac and other co-morbidities. There is an urgent need to discourage production and marketing all forms of ORS not in conformity with WHO approved LORS, under a slogan "One India, one ORS".

摘要

背景

国际儿科学会(IAP)上一次发布《腹泻综合管理指南》是在 2006 年,最近一次修订是在 2016 年。世界卫生组织(WHO)于 2002 年、印度政府于 2004 年建议使用低渗口服补液盐(ORS)作为所有年龄和所有类型脱水的通用补液溶液。然而,印度的 LORS 使用率仍然低得令人无法接受,仅为 51%,尽管人们对 ORS 的认识从 2005 年的 14%增加到 2015 年的 69%。市场上不同 ORS 配方和品牌的可用性也增加了混乱。

过程

印度儿科学会(IAP)召集了来自儿科学、儿科胃肠病学和营养领域的专家组成一个小组,更新儿童脱水管理方面的内容,特别是关于 LORS,并发布了当前的实践指南。委员会在 CIAP 总部举行了两次会议,审查了关于这一方面的所有已发表文献。简要介绍了相关内容,随后进行了讨论。电子邮件传阅了草案文件。所有相关的意见和建议都被纳入其中,以便就本实践指南达成共识。

目的

总结有关 ORT 的最新文献,为儿科医生,特别是在农村地区工作的儿科医生提供支持,增强对 LORS 使用的认识,以管理脱水。

建议

强调 LORS 的优势远远超过其局限性。只有通过在所有医学体系中提高公众和医疗保健提供者的认识,才能增加 LORS 的使用。ORS 在非腹泻疾病中管理脱水也同样有用。需要进一步开展更多研究,以修改 ORS,使其在新生儿、严重急性营养不良、肾衰竭、心脏和其他合并症中安全有效。迫切需要阻止生产和销售所有不符合世界卫生组织批准的 LORS 的 ORS 形式,口号是“一个印度,一种 ORS”。

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本文引用的文献

1
Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis.
Pediatrics. 2020 Apr;145(4). doi: 10.1542/peds.2019-3260. Epub 2020 Mar 4.
4
50 years of oral rehydration therapy: the solution is still simple.
Lancet. 2018 Aug 18;392(10147):536-538. doi: 10.1016/S0140-6736(18)31488-0. Epub 2018 Aug 16.
5
Management of Diarrhea - Changing Trends in Last 50 Years.
Indian Pediatr. 2018 Jan 15;55(1):63-65.
6
Oral rehydration of malnourished children with diarrhoea and dehydration: A systematic review.
Wellcome Open Res. 2017 Oct 27;2:66. doi: 10.12688/wellcomeopenres.12357.3. eCollection 2017.
7
Diagnostic accuracy of three clinical dehydration scales: a systematic review.
Arch Dis Child. 2018 Apr;103(4):383-388. doi: 10.1136/archdischild-2017-313762. Epub 2017 Oct 31.
8
Fever in Children: Pearls and Pitfalls.
Children (Basel). 2017 Sep 1;4(9):81. doi: 10.3390/children4090081.
10
Oral zinc for treating diarrhoea in children.
Cochrane Database Syst Rev. 2016 Dec 20;12(12):CD005436. doi: 10.1002/14651858.CD005436.pub5.

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