Department of Dental and Biomedical Materials Science, Graduate School of Biomedical Sciences, Nagasaki University.
Division of Chemistry and Materials Science, Graduate School of Engineering, Nagasaki University.
Dent Mater J. 2021 Jul 31;40(4):949-956. doi: 10.4012/dmj.2020-323. Epub 2021 Mar 13.
This study aimed to assess the mechanical and biological properties of bioactive glass (BG) coating on titanium (Ti). Bioinert Ti substrates were coated by BG to induce bioactivity to the surface. The sol-gel derived BG 58S sol was successfully prepared and coated on the abraded and blasted Ti surface using the sol-dip method. The characterization and cell study for all substrates' surface was carried out. Adhesion test confirmed that a firmly adhered BG coating layer was formed on the abraded and blasted Ti. The measured bonding strength between the coating and the blasted Ti substrate was the highest among all samples, which was 41.03±2.31 MPa. In-vitro cell viability and alkaline phosphatase activity (ALP) tests results also showed that BG coating on the Ti substrate improved the biological properties of the surface. The BG sol-dip coating method could be used to fabricate Ti substrate with a bioactive surface.
本研究旨在评估生物活性玻璃(BG)涂层在钛(Ti)上的力学和生物学性能。通过BG 涂层使生物惰性 Ti 基底表面具有生物活性。成功制备了溶胶-凝胶衍生的 BG 58S 溶胶,并通过溶胶浸渍法涂覆在研磨和喷砂处理的 Ti 表面上。对所有基底表面进行了特性和细胞研究。附着试验证实,研磨和喷砂处理的 Ti 表面形成了牢固附着的 BG 涂层。涂层与喷砂 Ti 基底之间测量的结合强度在所有样品中最高,为 41.03±2.31 MPa。体外细胞活力和碱性磷酸酶活性(ALP)测试结果也表明,BG 涂层可提高 Ti 基底表面的生物学性能。BG 溶胶浸渍涂层法可用于制备具有生物活性表面的 Ti 基底。