Urano Misugi, Denewar Fatmaelzahraa Abdelfattah, Okabe Ryo, Komatsu Hirokazu, Wanifuchi-Endo Yumi, Toyama Tatsuya, Shibamoto Yuta
Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuhocho, Mizuho-ku, Nagoya, Japan.
Department of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Radiol Case Rep. 2019 Mar 5;14(5):584-587. doi: 10.1016/j.radcr.2019.02.018. eCollection 2019 May.
Extramedullary plasmacytoma of the breast (EPB), a manifestation of multiple myeloma (MM), is very rare. It is important to recognize the imaging findings of EPB because it may be the first manifestation of relapsed MM. An 85-year-old woman presented with a lump in her right breast 4 years after the complete remission of MM. She underwent mammography and ultrasonography, which showed an oval circumscribed mass and an irregular circumscribed heterogeneous solid mass, respectively. Following ultrasound-guided vacuum-assisted breast biopsy, this lesion was confirmed to be EPB. Whole-body computed tomography showed multiple new osteolytic lesions and other multiple extramedullary lesions in addition to EPB in the right breast. The final diagnosis was relapsed MM with multiple extramedullary plasmacytoma.
乳腺髓外浆细胞瘤（EPB）是多发性骨髓瘤（MM）的一种表现形式，非常罕见。认识EPB的影像学表现很重要，因为它可能是复发性MM的首发表现。一名85岁女性在MM完全缓解4年后出现右乳肿块。她接受了乳房X线摄影和超声检查，分别显示为椭圆形边界清晰的肿块和不规则边界清晰的异质性实性肿块。在超声引导下进行真空辅助乳腺活检后，该病变被确诊为EPB。全身计算机断层扫描显示除右乳EPB外，还有多个新的溶骨性病变和其他多个髓外病变。最终诊断为复发性MM伴多发髓外浆细胞瘤。
