Department of Radiology, Advanced diagnostic and interventional radiology research center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Liver Transplantation Research Center, Imam-Khomeini Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
J Radiol Case Rep. 2021 Jan 31;15(1):11-20. doi: 10.3941/jrcr.v15i1.3822. eCollection 2021 Jan.
Pancreatic neuroendocrine tumors are rare neoplasms that comprise 1-2% of all pancreatic tumors. However, they are the second most common solid pancreatic neoplasms. They have a wide range of imaging appearances and they can show common to very rare imaging presentations. Most of the time they are solitary well-marginated enhancing solid mass arising in a certain aspect of the pancreas. We present a case report of a 41-year-old female who underwent clinical work-up for abdominal pain, loss of appetite and weight loss for the past year. Ultrasound, computed tomography, and magnetic resonance imaging show diffuse homogenous pancreatic enlargement without contour deformity or a focal mass. Lymphoma and autoimmune pancreatitis were suggested based on imaging findings but IGg4 level and other lab data were normal. Endoscopic ultrasonography confirmed the diffuse enlargement of the pancreas without peripheral structures involvement. The pathological results of multiple fine-needle aspiration biopsy from all parts of the enlarged pancreas revealed a low-grade neuroendocrine tumor.
胰腺神经内分泌肿瘤是罕见的肿瘤，占所有胰腺肿瘤的 1-2%。然而，它们是第二常见的胰腺实体肿瘤。它们的影像学表现多种多样，可以表现为常见到非常罕见的影像学表现。大多数情况下，它们是在胰腺的某个部位出现的边界清楚的单发强化实性肿块。我们报告了一例 41 岁女性的病例，她因腹痛、食欲不振和体重减轻在过去一年接受了临床检查。超声、计算机断层扫描和磁共振成像显示弥漫性均匀性胰腺增大，无轮廓畸形或局灶性肿块。根据影像学表现，提示为淋巴瘤和自身免疫性胰腺炎，但 IGg4 水平和其他实验室数据正常。内镜超声检查证实胰腺弥漫性肿大，无周围结构受累。从增大胰腺的各个部位进行的多次细针抽吸活检的病理结果显示为低级别神经内分泌肿瘤。
