表现为胰腺弥漫性肿大的胰腺腺泡细胞癌：两例报告及文献复习

Acinar cell carcinoma of the pancreas presenting as diffuse pancreatic enlargement: Two case reports and literature review.

作者信息

Luo Yaping, Hu Guilan, Ma Yanru, Guo Ning, Li Fang

机构信息

Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing, P.R. China.

出版信息

Medicine (Baltimore). 2017 Sep;96(38):e7904. doi: 10.1097/MD.0000000000007904.

DOI:10.1097/MD.0000000000007904

PMID:28930825

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5617692/

Abstract

RATIONALE

Pancreatic acinar cell carcinoma (ACC) is a rare malignant tumor of exocrine pancreas. It is typically a well-marginated large solid mass arising in a certain aspect of the pancreas. Diffuse involvement of ACC in the pancreas is very rare, and may simulate pancreatitis in radiological findings. We report 2 cases of ACC presenting as diffuse enlargement of the pancreas due to tumor involvement without formation of a distinct mass.

PATIENT CONCERNS

The patients consisted of a 41-year-old man with weight loss and a 77-year-old man who was asymptomatic.

DIAGNOSES

Computed tomography (CT) and 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT showed diffuse enlargement of the pancreas forming a sausage-like shape with homogenously increased FDG activity.

INTERVENTIONS

Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) biopsy of the pancreatic lesion was performed.

OUTCOMES

Histopathology results from the pancreas confirmed the diagnosis of pancreatic ACC.

LESSONS

Because diffuse enlargement of the pancreas is a common imaging feature of pancreatitis, recognition of this rare morphologic pattern of ACC is important for radiological diagnosis of this tumor.

摘要