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原发性气胸电视辅助胸腔镜检查术后的慢性胸痛和感觉异常

Chronic chest pain and paresthesia after video-assisted thoracoscopy for primary pneumothorax.

作者信息

Cattoni Maria, Rotolo Nicola, Mastromarino Maria Giovanna, Cardillo Giuseppe, Nosotti Mario, Mendogni Paolo, Rizzi Alessandro, Raveglia Federico, Siciliani Alessandra, Rendina Erino Angelo, Cagini Lucio, Matricardi Alberto, Filosso Pier Luigi, Passone Erika, Margaritora Stefano, Vita Maria Letizia, Bertoglio Pietro, Viti Andrea, Dominioni Lorenzo, Imperatori Andrea

机构信息

Center for Thoracic Surgery and Center for Minimally Invasive Surgery, Department of Medicine and Surgery, University of Insubria, Varese, Italy.

Unit of Thoracic Surgery, Regional Hospital San Camillo-Forlanini, Rome, Italy.

出版信息

J Thorac Dis. 2021 Feb;13(2):613-620. doi: 10.21037/jtd-20-2860.

Abstract

BACKGROUND

This study aims to identify clinical and surgical risk factors for chronic chest pain and paresthesia after video thoracoscopic surgery for primary spontaneous pneumothorax.

METHODS

We retrospectively collected the data of 1,178 consecutive patients <40-years-old undergoing video thoracoscopic surgery for primary spontaneous pneumothorax in 9 Italian centers in 2007-2017. Cases with <2-month follow-up were excluded, leaving 920 patients [80% male; median age: 21 (IQR, 18-27) years] for statistical analysis. The following risk factors for chronic chest pain and chronic paresthesia were assessed by univariable and multivariable Cox regression model: age, gender, cannabis smoking, video thoracoscopy ports number, pleurodesis technique (partial pleurectomy/pleural electrocauterization/pleural abrasion/talc poudrage), chest tube size (24/28 F), postoperative chest tube stay.

RESULTS

Blebs/bullae resection with pleurodesis was performed in 732 (80%) cases; pleurodesis alone in 188 (20%). During a median follow-up of 68 (IQR: 42-95) months, chronic chest pain developed in 8% of patients, chronic chest paresthesia in 22%; 0.5% of patients regularly assumed painkillers. Chronic chest pain was independently associated with partial pleurectomy/pleura abrasion (P<0.001) and postoperative chest tube stay (P=0.019). Chronic chest paresthesia was independently associated with pleurodesis by partial pleurectomy (P<0.001), chest tube stay (P=0.035) and 28 F chest tube (P<0.001).

CONCLUSIONS

After video thoracoscopic surgery for primary spontaneous pneumothorax, the incidence of chronic chest pain and paresthesia was significantly lower when pleurodesis was performed by pleural electrocauterization or talc poudrage, and chest tube was removed early. A 24 F chest tube was associated with lower risk of chronic chest paresthesia.

摘要

背景

本研究旨在确定原发性自发性气胸电视胸腔镜手术后慢性胸痛和感觉异常的临床及手术风险因素。

方法

我们回顾性收集了2007年至2017年期间在意大利9个中心连续接受原发性自发性气胸电视胸腔镜手术的1178例年龄小于40岁患者的数据。排除随访时间少于2个月的病例,剩余920例患者[80%为男性;中位年龄:21(四分位间距,18 - 27)岁]进行统计分析。通过单变量和多变量Cox回归模型评估以下慢性胸痛和慢性感觉异常的风险因素:年龄、性别、吸食大麻、电视胸腔镜手术切口数量、胸膜固定术技术(部分胸膜切除术/胸膜电灼术/胸膜摩擦术/滑石粉喷洒术)、胸管尺寸(24/28F)、术后胸管留置时间。

结果

732例(80%)患者行肺大疱切除术并胸膜固定术;188例(20%)仅行胸膜固定术。中位随访68(四分位间距:42 - 95)个月期间,8%的患者出现慢性胸痛,22%出现慢性胸部感觉异常;0.5%的患者经常服用止痛药。慢性胸痛与部分胸膜切除术/胸膜摩擦术(P<0.001)及术后胸管留置时间(P = 0.019)独立相关。慢性胸部感觉异常与部分胸膜切除术胸膜固定术(P<0.001)、胸管留置时间(P = 0.035)及28F胸管(P<0.001)独立相关。

结论

原发性自发性气胸电视胸腔镜手术后,采用胸膜电灼术或滑石粉喷洒术进行胸膜固定术且早期拔除胸管时,慢性胸痛和感觉异常的发生率显著降低。24F胸管与慢性胸部感觉异常风险较低相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afd1/7947510/0ff7a80a963c/jtd-13-02-613-f1.jpg

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