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[先天性主动脉瓣狭窄的瓣膜成形术]

[Valvuloplasty of congenital aortic stenosis].

作者信息

Rupprath G, Neuhaus K L

机构信息

Kinderklinik, Städtisches Krankenhaus Kaiserslautern.

出版信息

Herz. 1988 Feb;13(1):24-31.

PMID:3371843
Abstract

While percutaneous transluminal valvuloplasty has largely replaced open commissurotomy for congenital pulmonary valve stenosis, the experience with valvuloplasty for congenital aortic stenosis is limited. Between August, 1984 and June, 1987, a total of 27 valvuloplasties were carried out in 25 patients with congenital aortic stenosis; nine infants and 16 patients ranging in age from four to 25 years (mean age 13 +/- 6 years). The indication for valvuloplasty was established on the basis of congestive heart failure or severe stenosis in infants and in the presence of a pressure gradient in excess of 60 mm Hg in those older than one year of age. In eight infants, valvuloplasty reduced the transvalvular pressure gradient from 73 +/- 5 to 36 +/- 9 mm Hg (p less than 0.01; Figure 1). In the 16 patients older than one year of age, the pressure gradient was reduced from 93 +/- 25 to 49 +/- 15 mm Hg (p less than 0.01; Figure 2). The size of the balloon chosen was based on two-dimensional echocardiographic measurements of the aortic ring diameter from inner edge to inner edge. In infants, coronary artery dilating catheters and balloon catheters with an inflated diameter of 4.2 to 8 mm were employed; in children, the balloon diameter selected was 1 to 3 mm less than that of the valve ring diameter, in 15 cases a single-balloon catheter and in one a trefoil catheter. After puncture of the femoral artery and retrograde advancement of a guide-wire into the left ventricle, the balloon catheter was positioned via the guide-wire across the aortic valve.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

虽然经皮腔内瓣膜成形术在很大程度上已取代了先天性肺动脉瓣狭窄的开放性瓣膜交界切开术,但先天性主动脉瓣狭窄的瓣膜成形术经验有限。1984年8月至1987年6月期间,对25例先天性主动脉瓣狭窄患者共进行了27次瓣膜成形术;其中9例为婴儿,16例患者年龄在4至25岁之间(平均年龄13±6岁)。瓣膜成形术的指征是根据婴儿的充血性心力衰竭或严重狭窄以及1岁以上患者存在超过60 mmHg的压力阶差来确定的。在8例婴儿中,瓣膜成形术使跨瓣膜压力阶差从73±5 mmHg降至36±9 mmHg(p<0.01;图1)。在16例1岁以上的患者中,压力阶差从93±25 mmHg降至49±15 mmHg(p<0.01;图2)。所选用球囊的大小是根据主动脉环内径从内缘到内缘的二维超声心动图测量结果确定的。对于婴儿,使用冠状动脉扩张导管和膨胀直径为4.2至8 mm的球囊导管;对于儿童,所选球囊直径比瓣膜环直径小1至3 mm,15例使用单球囊导管,1例使用三叶导管。经股动脉穿刺并将导丝逆行推进至左心室后,通过导丝将球囊导管置于主动脉瓣处。(摘要截短至250字)

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