Neuhaus K L, Rupprath G
Medizinische Klinik II, Städtische Kliniken Kassel, West Germany.
Z Kardiol. 1987;76 Suppl 6:91-8.
Percutaneous balloon valvuloplasty was performed between 1984 and 1987 on 27 occasions in 25 patients with congenital aortic valve stenosis. Eight infants underwent ten dilatation procedures (two redilatations included); seven of these eight infants had critical aortic valve stenosis and one infant asymptomatic severe valve stenosis. One additional 5-day-old newborn died after left ventricular perforation, probably caused by the exchange wire during cardiac catherization immediately before valvuloplasty, despite emergency operation. The transvalvular pressure gradient was reduced in these eight infants from 73 +/- 5 to 36 +/- mmHg (p less than 0.01). Five infants were restudied after an interval of 3-6 months and redilatation performed in two patients with residual stenosis. One infant developed mild aortic incompetence and in one infant, mild aortic regurgitation following commissurotomy did not increase after two dilatation procedures at the age of 2 and 7 months. No aortic regurgitation was noted in the remaining 6 infants after dilatation. Valvuloplasty was also performed in 16 children and adolescents (4-25 years old, mean age 13 +/- 6 years) using balloons with inflated diameters 1 to 3 mm smaller than the aortic valve ring (15 single balloons, 1 trefoil balloon). Peak systolic pressure gradient decreased from 93 +/- 25 to 49 +/- mmHg (p less than 0.01). Mild aortic regurgitation was present in six patients (three following surgery) before dilatation and remained unchanged in five patients. In one patient, aortic incompetence increased slightly after valvuloplasty. Ten patients showed no evidence of aortic regurgitation after dilatation. Embolectomy of the femoral artery was performed in two patients 1-3 days after valvuloplasty. No further complications occurred.(ABSTRACT TRUNCATED AT 250 WORDS)
1984年至1987年间,对25例先天性主动脉瓣狭窄患者进行了27次经皮球囊瓣膜成形术。8名婴儿接受了10次扩张手术(包括2次再次扩张);这8名婴儿中有7名患有严重主动脉瓣狭窄,1名婴儿为无症状重度瓣膜狭窄。另有1名5日龄新生儿在瓣膜成形术前心脏导管插入术期间因交换导丝可能导致左心室穿孔,尽管进行了急诊手术仍死亡。这8名婴儿的跨瓣压差从73±5降至36±mmHg(p<0.01)。5名婴儿在3 - 6个月后接受复查,2例残留狭窄患者进行了再次扩张。1名婴儿出现轻度主动脉瓣关闭不全,1名婴儿在2个月和7个月时进行了两次扩张手术后,瓣膜切开术后的轻度主动脉瓣反流未加重。其余6名婴儿扩张后未发现主动脉瓣反流。还对16名儿童和青少年(4 - 25岁,平均年龄13±6岁)进行了瓣膜成形术,使用的球囊充气直径比主动脉瓣环小1至3毫米(15个单球囊,1个三叶球囊)。收缩压峰值梯度从93±25降至49±mmHg(p<0.01)。6例患者(3例术后)扩张前存在轻度主动脉瓣反流且5例未改变。1例患者瓣膜成形术后主动脉瓣关闭不全略有加重。10例患者扩张后未发现主动脉瓣反流证据。2例患者在瓣膜成形术后1 - 3天进行了股动脉栓子切除术。未发生进一步并发症。(摘要截选至250字)