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[先天性和后天性心脏病的血管成形术及经皮瓣膜成形术。短期和长期结果]

[Angioplasty and percutaneous valvuloplasty in congenital and acquired cardiopathies. Short- and long-term results].

作者信息

Ledesma M

机构信息

Depto. de Hemodinámica y fisiología pulmonar, Hospital General del Centro Médico La Raza, México, D.F.

出版信息

Arch Inst Cardiol Mex. 1988 Mar-Apr;58(2):145-58.

PMID:2969713
Abstract

Percutaneous transluminal balloon catheterization was performed in 38 patients, age 2 to 38 years (mean 13) between October, 1985 and May, 1987. Nineteen with pulmonary valve stenosis (PVS), three with small atrial septal defect (ASD) and one with ventricular septal defect (VSD); six with aortic valve stenosis (AVS); eight with Coarctation of the aorta (CoAo), in two with VSD and one with small ductus arteriosus; and four with rheumatic mitral stenosis (RMS). In PVS the peak systolic gradient (PSG) decreased significantly immediately after the procedure (92 +/- 40 vs 20 +/- 19 mmHg P less than 0.01). Nine patients were evaluated three months and seven one year later and no significant change occurred (19 +/- 11 and 20 +/- 19 mm Hg). The right ventricular systolic pressure (RVSP) and the ratio RVSP/left ventricular systolic pressure (LVSP) decreased immediately after the procedure (114 +/- 37 vs 69 +/- 36 mmHg P less than 0.15, and 0.98 +/- 0.29 vs 0.62 +/- 0.36, P less than 0.15). Three months later the RVSP and ratio RVSP/LVSP decreased more (57 +/- 16 mmHg, P less than 0.05, and 0.47 +/- 0.18, P less than 0.05) and one year later (54 +/- 27 mm Hg, P less than 0.05 and 0.46 +/- 0.24, P less than 0.05). In one case we repeated de dilatation one year later for restenosis. In CoAo PSG decreased immediately after dilation (59 +/- 21 vs 26 +/- 18 mmHg, P less than 0.1). Three months later the gradient was 38 +/- 20 mmHg. One patient was sent to surgery for significant residual gradient and one was dilated again 4 months after the first dilatation. One case was evaluated at cardiac catheterization one year later with gradient of 28 mmHg and blood pressure and femoral pulses were normal. In AVS PSG decrease immediately in all (91 +/- 25 vs 37 +/- 22 mmHg, P less than 0.02). Recatheterization in 4 patients three months later showed improvement in two. Two cases were sent to surgery for significant residual gradient. In these two patients we did not performed a dilatation because one had thrombosis in the puncture site and in the other we suspect subvalvular obstruction. The other two patients have shown clinical, echocardiographic and radiographic improvement.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

1985年10月至1987年5月期间,对38例年龄在2至38岁(平均13岁)的患者进行了经皮腔内球囊导管插入术。其中19例患有肺动脉瓣狭窄(PVS),3例患有小型房间隔缺损(ASD),1例患有室间隔缺损(VSD);6例患有主动脉瓣狭窄(AVS);8例患有主动脉缩窄(CoAo),其中2例合并VSD,1例合并小型动脉导管未闭;4例患有风湿性二尖瓣狭窄(RMS)。在PVS患者中,术后即刻收缩期峰值梯度(PSG)显著下降(92±40 vs 20±19 mmHg,P<0.01)。9例患者在术后3个月接受评估,7例在术后1年接受评估,未发生显著变化(19±11和20±19 mmHg)。术后即刻右心室收缩压(RVSP)和RVSP/左心室收缩压(LVSP)比值下降(114±37 vs 69±36 mmHg,P<0.15;0.98±0.29 vs 0.62±0.36,P<0.15)。3个月后,RVSP和RVSP/LVSP比值进一步下降(57±16 mmHg,P<0.05;0.47±0.18,P<0.05),1年后(54±27 mmHg,P<0.05;0.46±0.24,P<0.05)。1例患者在术后1年因再狭窄接受了再次扩张。在CoAo患者中,扩张后即刻PSG下降(59±21 vs 26±18 mmHg,P<0.1)。3个月后梯度为38±20 mmHg。1例患者因残留梯度明显而接受手术,1例在首次扩张后4个月再次进行扩张。1例患者在术后1年进行心脏导管检查评估,梯度为28 mmHg,血压和股动脉搏动正常。在AVS患者中,所有患者的PSG均即刻下降(91±25 vs 37±22 mmHg,P<0.02)。4例患者在术后3个月再次进行导管检查,其中2例病情改善。2例患者因残留梯度明显而接受手术。在这2例患者中,1例因穿刺部位血栓形成未进行扩张,另1例怀疑有瓣下梗阻未进行扩张。另外2例患者在临床、超声心动图和影像学方面均有改善。(摘要截选至400字)

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