Chigladze Maka
Ivane Javakhishvili Tbilisi State University, Tbilisi, Georgia.
Glob Pediatr Health. 2021 Feb 27;8:2333794X21999149. doi: 10.1177/2333794X21999149. eCollection 2021.
The research aimed at studying the mother's social-hygienic and medical biological risk factors and determining their predictive value. The retrospective case-control study was conducted with 142 pregnant women participating in it. In the case group there were involved 92 mothers whose pregnancy was completed by the birth of a newborn baby suffering from the intrauterine growth restriction. The control group was made of 50 pregnant women, whose pregnancy was completed by the birth of a healthy neonate. The research resulted in specifying the risk factors of high priority: the low standards of living (OR 3.61), chronic stress (OR-3.06), sleeping disorder (OR-3.33) and poor nutrition (OR-3.81). As regards the coexisting pathology the following was revealed: endocrine pathology (OR-3.27), ischemic heart disease (OR-4.35), arterial hypertension (OR-6.47), iron deficiency anemia (OR-4.11), pathology of respiratory system (OR-3.42), chronic genital inflammatory and infectious processes. The preeclampsia (92%) and low amniotic fluid (89%) were detected to have the high predictive value. The awareness of risk factors allows us to employ the timely measures for the reduction of negative impact on the fetus and neonate.
该研究旨在探讨母亲的社会卫生和医学生物风险因素，并确定其预测价值。对142名参与研究的孕妇进行了回顾性病例对照研究。病例组包括92名母亲，她们的妊娠结局是产下患有宫内生长受限的新生儿。对照组由50名孕妇组成，她们的妊娠结局是产下健康的新生儿。研究明确了高优先级的风险因素：生活水平低（比值比3.61）、慢性应激（比值比3.06）、睡眠障碍（比值比3.33）和营养不良（比值比3.81）。关于并存的病理情况，发现了以下情况：内分泌病理（比值比3.27）、缺血性心脏病（比值比4.35）、动脉高血压（比值比6.47）、缺铁性贫血（比值比4.11）、呼吸系统病理（比值比3.42）、慢性生殖器炎症和感染性疾病。子痫前期（92%）和羊水过少（89%）被检测出具有较高的预测价值。对风险因素的认识使我们能够及时采取措施，减少对胎儿和新生儿的负面影响。
