Ernst Sinja Alexandra, Brand Tilman, Reeske Anna, Spallek Jacob, Petersen Knud, Zeeb Hajo
Leibniz-Institute for Prevention Research and Epidemiology-BIPS, Bremen, Germany.
Federal Institute for Occupational Safety and Health (BAuA), Dortmund, Germany.
Biomed Res Int. 2017;2017:1746146. doi: 10.1155/2017/1746146. Epub 2017 Apr 4.
. To identify care-related and maternal risk factors for the antenatal nondetection of IUGR. . In this hospital-based case-control study we compared antenatally undetected IUGR neonates (cases) to detected IUGR neonates (controls). Data were collected using newborn documentation sheets and standardized personal interviews with the mothers. We calculated antenatal detection rates and used uni- and multivariable logistic regression models to assess the association of antenatal nondetection of IUGR and maternal and care-related factors. . A total of 161 neonates from three hospitals were included in the study. Suboptimal fetal growth was identified antenatally in = 77 pregnancies while in = 84 it was not detected antenatally (antenatal detection rate: 47.8%). Severity of IUGR, maternal complications, and a Doppler examination during the course of pregnancy were associated with IUGR detection. We did not find statistically significant differences regarding parental socioeconomic status and maternal migration background. . In our study, about half of all pregnancies affected by suboptimal growth remained undetected. Future in-depth studies with larger study populations should further examine factors that could increase antenatal detection rates for IUGR.
确定产前未检测出胎儿生长受限（IUGR）的护理相关及母体风险因素。在这项基于医院的病例对照研究中，我们将产前未检测出的IUGR新生儿（病例组）与检测出的IUGR新生儿（对照组）进行了比较。数据通过新生儿记录单以及对母亲进行标准化的个人访谈收集。我们计算了产前检测率，并使用单变量和多变量逻辑回归模型来评估产前未检测出IUGR与母体及护理相关因素之间的关联。该研究共纳入了来自三家医院的161名新生儿。在77例妊娠中产前确定存在胎儿生长发育欠佳，而在84例中产前未检测出（产前检测率：47.8%）。IUGR的严重程度、母体并发症以及孕期进行的多普勒检查与IUGR检测相关。我们未发现父母社会经济地位和母体移民背景存在统计学上的显著差异。在我们的研究中，约一半受生长发育欠佳影响的妊娠仍未被检测出。未来对更大研究人群进行的深入研究应进一步探究可提高IUGR产前检测率的因素。
