Lopes de Faria J, Nunes P H
Department of Pathology, Hospital das Clinicas, Unicamp, Campinas, SP, Brazil.
Histopathology. 1988 Jan;12(1):85-94. doi: 10.1111/j.1365-2559.1988.tb01919.x.
Two cases of basosquamous cell carcinoma of the skin with lymph node, lung and bone metastases are reported. Metastases occurred 4 and 7 years after identification of the primary tumour. Both the primary and metastatic lesions had areas of typical basal cell carcinoma and squamous cell carcinoma and also intermediate carcinomatous tissue. In the bone metastasis of one case there were rudimentary hair follicles and areas of matrical differentiation. These cases further support the existence of basosquamous cell carcinoma and emphasize its metastatic potential.
报告了两例皮肤基底鳞状细胞癌伴淋巴结、肺和骨转移的病例。转移发生在原发性肿瘤确诊后4年和7年。原发性和转移性病变均有典型的基底细胞癌和鳞状细胞癌区域,以及中间性癌组织。在其中一例的骨转移中,有发育不全的毛囊和基质分化区域。这些病例进一步支持了基底鳞状细胞癌的存在,并强调了其转移潜能。