Euromov, University of Montpelier, Montpelier, France.
Department of Behavioral Sciences and Social Medicine, College of Medicine, Florida State University, Tallahassee, Florida, USA.
J Gerontol B Psychol Sci Soc Sci. 2021 Nov 15;76(10):2023-2028. doi: 10.1093/geronb/gbab047.
The motoric cognitive risk (MCR) syndrome, characterized by cognitive complaints and slower gait speed, is a predementia syndrome associated with dementia and mortality risk. The present study examined whether subjective age, that is, how old or young individuals feel relative to their chronological age, is related to concurrent and incident MCR syndrome. A relation between subjective age and MCR will inform knowledge on psychological factors related to dementia risk, identify who is at greater risk, and suggest a potential target of intervention.
The study sample was composed of 6,341 individuals aged 65-107 years without dementia from the Health and Retirement Study, a longitudinal study of adults aged 50 years and older. Participants completed measures of subjective age, cognitive complaints, and gait speed and provided information on demographic factors, cognition, physical activity, depressive symptoms, and body mass index (BMI) at baseline in 2008/2010. Incident MCR was assessed 4 and 8 years later.
Controlling for demographic factors, an older subjective age was related to more than 60% higher likelihood of MCR at baseline and to around 50% higher risk of incident MCR over time. These associations remained significant when cognition, physical inactivity, depressive symptoms, and BMI were included in the analytic models.
This study provides evidence that how old individuals feel is related to concurrent and incident MCR beyond the effect of chronological age, other demographic factors, physical inactivity, depressive symptoms, BMI, and cognitive functioning.
运动认知风险（MCR）综合征的特征是认知主诉和更慢的步速，是一种与痴呆和死亡风险相关的前驱痴呆综合征。本研究探讨了主观年龄（即个体相对于实际年龄的感觉年龄）是否与同时发生和随后发生的 MCR 综合征有关。主观年龄与 MCR 之间的关系将为与痴呆风险相关的心理因素提供知识，确定谁面临更大的风险，并提出潜在的干预目标。
该研究样本由来自健康与退休研究（一项针对 50 岁及以上成年人的纵向研究）的 6341 名无痴呆的 65-107 岁个体组成。参与者完成了主观年龄、认知主诉和步速的测量，并在 2008/2010 年基线时提供了人口统计学因素、认知、身体活动、抑郁症状和体重指数（BMI）的信息。在 4 年和 8 年后评估了 MCR 的新发情况。
控制人口统计学因素后，主观年龄越大，基线时 MCR 的发生可能性就高出 60%以上，随着时间的推移，MCR 的发生风险高出约 50%。当将认知、身体活动不足、抑郁症状和 BMI 纳入分析模型时，这些关联仍然具有统计学意义。
本研究提供了证据表明，个体的感觉年龄与同时发生和随后发生的 MCR 有关，这种关系超出了实际年龄、其他人口统计学因素、身体活动不足、抑郁症状、BMI 和认知功能的影响。
