Department of Psychiatry & Behavioral Sciences, Medical University of South Carolina.
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University.
Psychol Addict Behav. 2021 Feb;35(1):29-41. doi: 10.1037/adb0000700.
To understand how interpersonal trauma (IPT), stress response, and drinking to cope converge to predict stress-induced drinking, a risk factor for alcohol use disorder.
Young adults with no substance use disorder were classified into three trauma history groups: (a) IPT with PTSD (n = 27), (b) IPT without PTSD (n = 35), and (c) Control (no trauma-history/no PTSD; n = 36). Participants completed a baseline assessment, including a structured clinical interview, to confirm PTSD diagnosis, followed by the Trier Social Stressor Task (TSST) and an alcohol use task. Subjective units of distress and blood serum cortisol were collected at standardized timepoints throughout the tasks.
In all three groups (PTSD, IPT, control), males consumed more alcohol in the lab than females. Participants in the PTSD group had significantly higher drinking to cope motives, which were associated with greater subjective reactivity; however, neither drinking to cope motives nor subjective reactivity to the TSST predicted post-stressor alcohol consumption for those with PTSD.
The interplay among trauma history, stress, and drinking among young adults is nuanced; additional lab-based studies are needed to further clarify the nuanced connection between trauma history, acute stress reactions, and alcohol use. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
了解人际创伤（IPT）、应激反应和饮酒应对如何共同作用，预测应激诱导性饮酒，这是酒精使用障碍的一个风险因素。
无物质使用障碍的年轻成年人被分为三组创伤史：（a）伴有 PTSD 的 IPT（n=27）、（b）无 PTSD 的 IPT（n=35）和（c）对照组（无创伤史/无 PTSD；n=36）。参与者完成基线评估，包括结构化临床访谈，以确认 PTSD 诊断，然后进行特里尔社会应激测试（TSST）和饮酒任务。在任务的各个标准化时间点采集主观不适单位和血清皮质醇。
在所有三组（PTSD、IPT、对照组）中，男性在实验室中的饮酒量均高于女性。PTSD 组的参与者具有更高的饮酒应对动机，这与更大的主观反应有关；然而，无论是 PTSD 患者的饮酒应对动机还是对 TSST 的主观反应都不能预测应激后的饮酒量。
在年轻成年人中，创伤史、压力和饮酒之间的相互作用是复杂的；需要更多的实验室研究来进一步阐明创伤史、急性应激反应和饮酒之间的微妙联系。
