Department of Otorhinolaryngology-Head and Neck Surgery, 159397Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Ear Nose Throat J. 2022 Feb;101(2_suppl):17S-23S. doi: 10.1177/0145561321999262. Epub 2021 Mar 15.
The purpose of this study is to review the differences between continuous wave (CW) and UltraPulse (UP) on thermal damage of the laser with different power.
Four adult beagle dogs underwent transoral laser microsurgery (TLM) using CO laser. The laser emission mode and power was CW (3 W, 5 W, and 8 W) and UP (3 W and 5 W), respectively. The tissue from 4 animals was evaluated histologically on postoperative days 1 and 3. The thermal damage of the laser was measured using slide scan system via SlideViewer version 1.5.5.2 software.
All dogs underwent TLM uneventfully. Under microscope examined, the laser damage area was composed of 2 parts: the vaporized zone (VPZ) and thermal damage area. The thermal damage area can be divided into thermal coagulative necrosis area (TCN) and hydropic degeneration area. The width of VPZ and TCN in UP mode was less than that in CW mode ( < .01). The data indicate that lower laser power created less thermal damage ( < .01). In addition, the width of VPZ on postoperative day 3 was less than that on postoperative day 1 ( < .01).
CO laser with UP and lower power could decrease the laser thermal damage and may offer more prompt wound healing.
本研究旨在比较不同功率连续波（CW）和超脉冲（UP）激光对组织热损伤的差异。
4 只成年比格犬接受 CO2 激光经口激光微创手术（TLM）。激光发射模式和功率分别为 CW（3 W、5 W 和 8 W）和 UP（3 W 和 5 W）。术后第 1、3 天，4 只动物的组织标本行组织学评估。采用 SlideViewer 1.5.5.2 软件的 SlideScan 系统测量激光热损伤。
所有犬均顺利完成 TLM。显微镜下，激光损伤区由 2 部分组成：汽化区（VPZ）和热损伤区。热损伤区可分为热凝固性坏死区（TCN）和水肿变性区。UP 模式下 VPZ 和 TCN 的宽度均小于 CW 模式（ <.01）。数据表明，较低的激光功率造成的热损伤较小（ <.01）。此外，术后第 3 天 VPZ 的宽度小于术后第 1 天（ <.01）。
CO2 激光的 UP 模式和较低功率可减少激光热损伤，可能提供更迅速的伤口愈合。
