Department of Sociology, University of Oxford, Oxford, UK.
Department of Brain Sciences, Imperial College London, London, UK.
J Psychopharmacol. 2021 Apr;35(4):447-452. doi: 10.1177/0269881121996863. Epub 2021 Mar 9.
In recent years, there has been significant research on the mental health effects of classic psychedelic use, but there is very little evidence on how classic psychedelics might influence physical health.
The purpose of the present study was to investigate the associations between lifetime classic psychedelic use and markers of physical health.
Using data from the National Survey on Drug Use and Health (2015-2018) with 171,766 (unweighted) adults aged 18 or above in the United States, the current study examined the associations between lifetime classic psychedelic use and three markers of physical health (self-reported overall health, body mass index, and heart condition and/or cancer in the past 12 months) while controlling for a range of covariates.
Respondents who reported having tried a classic psychedelic at least once in their lifetime had significantly higher odds of greater self-reported overall health and significantly lower odds of being overweight or obese versus having a normal weight. The association between lifetime classic psychedelic use and having a heart condition and/or cancer in the past 12 months approached conventional levels of significance, with lower odds of having a heart condition and/or cancer in the past 12 months for respondents who had tried a classic psychedelic at least once.
The results of the present study suggest that classic psychedelics may be beneficial to physical health. Future research should investigate the causal effects of classic psychedelics on physical health and evaluate possible mechanisms.
近年来，人们对经典迷幻药物使用对心理健康的影响进行了大量研究，但关于经典迷幻药物如何影响身体健康的证据却非常有限。
本研究旨在调查一生中使用经典迷幻药物与身体健康指标之间的关联。
本研究使用了美国国家药物使用与健康调查（2015-2018 年）的数据，该调查涵盖了 171766 名（未经加权）年龄在 18 岁及以上的成年人，研究考察了一生中使用经典迷幻药物与身体健康的三个指标（自我报告的整体健康状况、体重指数以及过去 12 个月内的心脏状况和/或癌症）之间的关联，同时控制了一系列协变量。
报告一生中至少尝试过一次经典迷幻药物的受访者，其自我报告的整体健康状况显著更好，超重或肥胖的可能性显著降低，体重正常的可能性更高。一生中使用经典迷幻药物与过去 12 个月内患有心脏疾病和/或癌症之间的关联接近传统的显著性水平，与一生中至少尝试过一次经典迷幻药物的受访者相比，过去 12 个月内患有心脏疾病和/或癌症的可能性较低。
本研究结果表明，经典迷幻药物可能对身体健康有益。未来的研究应调查经典迷幻药物对身体健康的因果影响，并评估可能的机制。
