Rhinology Study Group of the Young-Otolaryngologists of the International Federations of Otorhinolaryngological Societies (YO-IFOS), Paris, France.
Service of Otolaryngology, Hospital Complex of Santiago de Compostela, Santiago, Spain.
Laryngoscope. 2022 Jan;132(1):6-16. doi: 10.1002/lary.29509. Epub 2021 Mar 15.
Nasal diseases are among the main motives for the early discontinuation of continuous positive airway pressure therapy and for long-term therapeutic compliance with mandibular advancement device. Although our clinical experience leads us to the belief that recumbency impacts nasal airflow in some patient populations, there is no consensus regarding the magnitude of this effect and the specific group of patients who are the most affected by this condition. In this study, we conducted a meta-analysis to assess the effect of the recumbent position on nasal resistance and nasal airflow.
PubMed (Medline), Cochrane Library, EMBASE, Scopus, and SciELO databases were checked for relevant studies by two members of the YO-IFOS study group. The two authors extracted the data. The main outcome was expressed as the difference between nasal resistance and nasal airflow before and after recumbency.
Nine studies with a total population of 291 individuals were included in the meta-analysis for nasal resistance after recumbency. We found a statistically significant difference in nasal airway resistance of -0.18 Pa sec/cm as compared to before and after recumbency through rhinomanometry (RMM) analysis. A subgroup analysis revealed a variation of -0.20 Pa sec/cm for patients with snoring or sleep apnea and - 0.10 Pa sec/cm for healthy individuals. Regarding nasal airflow measured with RMM, three studies (n = 32) in asymptomatic controls revealed a statistically significant difference of 47.33 ml/sec.
Recumbency increases nasal resistance and diminishes nasal airflow. This finding is of utmost importance in snorers and sleep apnea patients. Laryngoscope, 132:6-16, 2022.
鼻部疾病是导致持续气道正压通气治疗早期中断和长期治疗依从性差的主要原因之一。尽管我们的临床经验使我们相信卧位会影响某些患者群体的鼻气流，但对于这种影响的程度以及最受影响的特定患者群体，尚未达成共识。在这项研究中，我们进行了一项荟萃分析，以评估卧位对鼻阻力和鼻气流的影响。
由 YO-IFOS 研究小组成员中的两名成员检查了 PubMed（Medline）、Cochrane 图书馆、EMBASE、Scopus 和 SciELO 数据库中与研究相关的文献。两位作者提取了数据。主要结局指标表示卧位前后鼻阻力的差异。
9 项研究共纳入 291 例患者，纳入了卧位后鼻阻力的荟萃分析。我们通过鼻阻力测量（RMM）分析发现，与卧位前和卧位后相比，鼻气道阻力存在统计学显著差异，为-0.18 Pa sec/cm。亚组分析显示，打鼾或睡眠呼吸暂停患者的差异为-0.20 Pa sec/cm，健康个体的差异为-0.10 Pa sec/cm。关于用 RMM 测量的鼻气流，32 例无症状对照者的 3 项研究显示，差异具有统计学意义，为 47.33 ml/sec。
卧位会增加鼻阻力并减少鼻气流。这一发现对打鼾和睡眠呼吸暂停患者尤为重要。《喉镜》，132:6-16,2022。
