Valbonesi M, Torre G C, Capra C, Frisoni R, Testa R, Zia S, Ferrari M
Immunohematology Services, San Martino University Hospital, Genova, Italy.
Int J Artif Organs. 1988 Mar;11(2):134-8.
Refractory ascites is an infrequent complication of cirrhosis. Paracentesis and ultrafiltration of the ascitic fluid with intravenous or intraperitoneal reinfusion of the concentrated ascites has been used as therapy for this condition since 1971. The technique is cumbersome and has high morbidity and mortality rates, even if effective. In this paper we describe a new technique that couples secondary filtration for the removal of macromolecules, with ultrafiltration of ascitic fluid. In its very first application 6 patients underwent 8 treatments. No adverse effect was observed and clinical efficacy was good. Up to 60 g of albumin can be saved in a single session lasting less than 2 hours.
顽固性腹水是肝硬化罕见的并发症。自1971年以来，腹腔穿刺放液并对腹水进行超滤，然后将浓缩腹水静脉内或腹腔内回输，一直被用作这种病症的治疗方法。该技术操作繁琐，即使有效，其发病率和死亡率也很高。在本文中，我们描述了一种新技术，该技术将用于去除大分子的二级过滤与腹水超滤相结合。在其首次应用中，6名患者接受了8次治疗。未观察到不良反应，临床疗效良好。在不到2小时的单次治疗中最多可节省60克白蛋白。
