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持续超滤-腹水回输治疗顽固性腹水

Treatment of resistant ascites by continuous ultrafiltration--reinfusion of ascitic fluid.

作者信息

Villeneuve J P, Thuot C, Marleau D, Joly J G, Huet P M, Viallet A

出版信息

Can Med Assoc J. 1977 Dec 3;117(11):1296-8.

Abstract

Eight patients with diuretic-resistant ascites due to cirrhosis were treated by reinfusion of concentrated ascitic fluid. In 11 procedures, with a mean duration of 21.9 hours, weight loss averaged 14.8 kg. Complications during reinfusion included septicemia in 1 procedure, left-sided heart failure in 5, pyrexia in 7 and coagulation abnormalities in 10. Ascites recurred within 2 months after reinfusion in all but one patient. Although this technique is an efficient and inexpensive method of treatment of ascites, it does not appear indicated in patients with cirrhosis and resistant ascites in view of the possibly serious complications associated with reinfusion and the poor long-term results.

摘要

8例因肝硬化导致利尿剂抵抗性腹水的患者接受了浓缩腹水回输治疗。在11次治疗过程中,平均时长为21.9小时,体重减轻平均为14.8千克。回输过程中的并发症包括1例发生败血症,5例出现左侧心力衰竭,7例发热,10例有凝血异常。除1例患者外,所有患者在回输后2个月内腹水复发。尽管该技术是一种治疗腹水的有效且廉价的方法,但鉴于回输可能带来的严重并发症以及较差的长期效果,对于肝硬化和顽固性腹水患者似乎并不适用。

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[Chronic fibrinolysis in alcoholic cirrhosis].
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