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[心血管-踝部血管指数(CAVI)在心血管疾病和2型糖尿病患者主血管病变的诊断、风险及严重程度评估中的应用]

[Cardio-ankle vascular index (CAVI) in diagnostics, risk and severity evaluation of magistral vessels lesion in patients with cardio-vascular diseases and type 2 diabetes].

作者信息

Verner V A, Mel'nik M V, Knjazeva S A

机构信息

Sechenov First Moscow State Medical University (Sechenov University).

出版信息

Ter Arkh. 2021 Jan 10;93(1):87-93. doi: 10.26442/00403660.2021.01.200599.

DOI:10.26442/00403660.2021.01.200599
PMID:33720632
Abstract

Assesment of arterial stiffness the substantional prognostic factor for evaluating complications of cardiovascular diseases (CVD) in patients with atherosclerosis, hypertension and type 2 diabetes, may be performed using different parameters, including cardio-ankle vascular index (CAVI). The main purpose of this review is to analyze data from studies where CAVI is used to test the arterial wall stiffness in magistral vessels. CAVI measurement is non-invasive and performed by portable devices which makes it comfortable for ambulatory use in patients who come for a check-up and also in those who already are hospitalized. It does not require any special knowledge from investigator and the test lasts a couple of minutes long. CAVI does not depend on blood pressure changes and is more specific in structural changes of arterial wall assessment than brachial-ankle pulse wave velocity (baPWV). CAVI shows considerable correlation with markers of CVD like atherosclerotic plaques in vessels, diastolic disfunction of left ventricle and angina pectoris. CAVI may be used for early monitoring and assessing the lesions of target organs in patients with atherosclerosis, chronic hypertension and type 2 diabetes. Establishing CAVI as a standart parameter in assessing patients who are at risk of CVD can help to improve complications prevention, reduce mortality and prolong their lifespan.

摘要

评估动脉僵硬度是评估动脉粥样硬化、高血压和2型糖尿病患者心血管疾病(CVD)并发症的重要预后因素,可使用不同参数进行评估,包括心踝血管指数(CAVI)。本综述的主要目的是分析使用CAVI检测主血管动脉壁僵硬度的研究数据。CAVI测量是非侵入性的,由便携式设备完成,这使得它便于在前来体检的患者以及已住院的患者中进行门诊使用。它不需要研究者具备任何特殊知识,测试持续几分钟。CAVI不依赖于血压变化,在评估动脉壁结构变化方面比臂踝脉搏波速度(baPWV)更具特异性。CAVI与CVD标志物如血管中的动脉粥样硬化斑块、左心室舒张功能障碍和心绞痛有显著相关性。CAVI可用于对动脉粥样硬化、慢性高血压和2型糖尿病患者的靶器官病变进行早期监测和评估。将CAVI确立为评估CVD风险患者的标准参数有助于改善并发症预防、降低死亡率并延长其寿命。

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