天花粉蛋白、α-苦瓜素和β-苦瓜素：堕胎蛋白与核糖体失活蛋白的一致性
Trichosanthin, alpha-momorcharin and beta-momorcharin: identity of abortifacient and ribosome-inactivating proteins.
作者信息
Yeung H W, Li W W, Feng Z, Barbieri L, Stirpe F
机构信息
Department of Biochemistry, Chinese University of Hong Kong, Shatin, N.T.
出版信息
Int J Pept Protein Res. 1988 Mar;31(3):265-8. doi: 10.1111/j.1399-3011.1988.tb00033.x.
The abortifacient proteins trichosanthin, alpha-momorcharin and beta-momorcharin at nM concentrations inhibit cell-free protein synthesis. The momorcharins and the ribosome-inactivating proteins isolated from Momordica charantia seeds cross-react with the respective antisera. The ribosome-inactivating proteins saporins, pokeweed antiviral protein (PAP) and, to a lesser extent, gelonin have abortifacient activity on pregnant mice.
天花粉蛋白、α-苦瓜素和β-苦瓜素等堕胎蛋白在纳摩尔浓度下可抑制无细胞蛋白质合成。从苦瓜种子中分离出的苦瓜素和核糖体失活蛋白与各自的抗血清发生交叉反应。核糖体失活蛋白皂草素、商陆抗病毒蛋白（PAP）以及程度较轻的相思豆毒蛋白对怀孕小鼠具有堕胎活性。
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