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Serological survey following SARS-COV-2 outbreaks at long-term care facilities in metro Vancouver, British Columbia: Implications for outbreak management and infection control policies.卑诗省大温哥华地区长期护理机构发生 SARS-CoV-2 疫情后的血清学调查:对疫情管理和感染控制政策的启示。
Am J Infect Control. 2021 May;49(5):649-652. doi: 10.1016/j.ajic.2020.10.009. Epub 2020 Oct 18.
2
Clinical and laboratory evaluation of SARS-CoV-2 lateral flow assays for use in a national COVID-19 seroprevalence survey.用于全国 COVID-19 血清流行率调查的 SARS-CoV-2 侧向流动检测的临床和实验室评估。
Thorax. 2020 Dec;75(12):1082-1088. doi: 10.1136/thoraxjnl-2020-215732. Epub 2020 Aug 12.
3
Evaluation of Six Commercial Mid- to High-Volume Antibody and Six Point-of-Care Lateral Flow Assays for Detection of SARS-CoV-2 Antibodies.评估六种中高容量抗体商业试剂盒和六种即时侧向流动检测试剂盒用于 SARS-CoV-2 抗体检测。
J Clin Microbiol. 2020 Sep 22;58(10). doi: 10.1128/JCM.01361-20.
4
Four point-of-care lateral flow immunoassays for diagnosis of COVID-19 and for assessing dynamics of antibody responses to SARS-CoV-2.四种即时侧向流动免疫分析法,用于诊断 COVID-19 并评估针对 SARS-CoV-2 的抗体反应动态。
J Infect. 2020 Sep;81(3):435-442. doi: 10.1016/j.jinf.2020.06.023. Epub 2020 Jun 15.
5
Real-time PCR-based SARS-CoV-2 detection in Canadian laboratories.基于实时 PCR 的加拿大实验室中 SARS-CoV-2 的检测。
J Clin Virol. 2020 Jul;128:104433. doi: 10.1016/j.jcv.2020.104433. Epub 2020 May 13.

即时检验侧向流动试验对毛细血管血与静脉血进行严重急性呼吸综合征冠状病毒2抗体血清学检测的比较分析

Comparative Analysis of Capillary vs Venous Blood for Serologic Detection of SARS-CoV-2 Antibodies by RPOC Lateral Flow Tests.

作者信息

Morshed Muhammad, Sekirov Inna, McLennan Meghan, Levett Paul N, Chahil Navdeep, Mak Annie, Carruthers Erin, Pidduck Tamara, Kustra Jesse, Laley Jonathan, Lee Min-Kuang, Chu Kenneth, Burgess Fred, Vijh Rohit, Willis Lori, Wada Ray, Blancaflor Rosemarie, Boraston Suni, Hayden Althea, Krajden Mel

机构信息

British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

Open Forum Infect Dis. 2021 Jan 28;8(3):ofab043. doi: 10.1093/ofid/ofab043. eCollection 2021 Mar.

DOI:10.1093/ofid/ofab043
PMID:33723509
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7928643/
Abstract

A comparison of rapid point-of-care serology tests using finger prick and venous blood was done on 278 participants. In a laboratory setting, immunoglobulin G (IgG) sensitivity neared 100%; however, IgG sensitivity dramatically dropped (82%) in field testing. Possible factors include finger prick volume variability, hemolysis, cassette readability, and operator training.

摘要

对278名参与者进行了使用手指针刺血和静脉血的即时快速血清学检测比较。在实验室环境中,免疫球蛋白G(IgG)敏感性接近100%;然而,在现场检测中IgG敏感性大幅下降(82%)。可能的因素包括手指针刺血量的变异性、溶血、检测卡的可读性以及操作人员的培训。