Grigore T. Popa Univ. of Medicine and Pharmacy, Institute of Gastroenterol and Hepatol, St. Spiridon Univ. Hospital, Iași, Romania. .
Grigore T. Popa Univ. of Medicine and Pharmacy, Institute of Gastroenterol and Hepatol, St. Spiridon Univ. Hospital, Iași, Romania.
J Gastrointestin Liver Dis. 2021 Mar 13;30(1):147-163. doi: 10.15403/jgld-3297.
Fecal microbiota transplantation involves the infusion of intestinal microorganisms via the transfer of a stool from a healthy individual into a diseased individual, with the intent of restoring normal intestinal flora. Fecal transplant is proposed for the treatment of refractory Clostridioides difficile infection. At present, recurrent Clostridioides difficile infection is the only indication supported by solid scientific evidence. Regulations by healthcare authorities vary among different countries. Considering that Romania does not have an available national guideline to offer standardization, this paper aimed to create a national fecal microbiota transplantation guideline concerning indications, techniques and donor screening, developed by international and local scientific working groups.
粪便微生物群移植涉及通过将来自健康个体的粪便转移到患病个体中，输注肠道微生物，目的是恢复正常的肠道菌群。粪便移植被提议用于治疗难治性艰难梭菌感染。目前，复发性艰难梭菌感染是唯一有确凿科学证据支持的适应证。不同国家的医疗保健当局的规定有所不同。考虑到罗马尼亚没有可用的国家指南提供标准化，本文旨在由国际和本地科学工作组制定关于适应证、技术和供体筛选的国家粪便微生物群移植指南。
