软骨干细胞标志物及诱导分化的研究进展。
Research advances in cartilage stem cells markers and induced differentiation.
机构信息
Dept. of Stomatological, Taizhou Central Hospital (Taizhou University Hospital), Taizhou 318000, China.
College of Stomatology, Zhejiang Chinese Medical University, Hangzhou 310053, China.
出版信息
Hua Xi Kou Qiang Yi Xue Za Zhi. 2021 Feb 1;39(1):108-114. doi: 10.7518/hxkq.2021.01.017.
Abstract
Cartilage stem cells (CSCs) are cells that self-proliferate, have surface antigen expression, and have multidirectional differentiation potential in the articular cartilage. CSCs, as an ideal source of stem cells, has a good application prospect in stem cell therapy. This article reviews the CSCs markers, cartilage differentiation signaling pathway, and clinical treatment of osteoarthritis.
摘要
软骨干细胞（CSCs）是一种自我增殖、具有表面抗原表达、并在关节软骨中具有多向分化潜能的细胞。CSCs 作为一种理想的干细胞来源，在干细胞治疗中有很好的应用前景。本文就 CSCs 的标志物、软骨分化信号通路以及骨关节炎的临床治疗进行综述。
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