Buehl Wolf, Findl Oliver
Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
J Cataract Refract Surg. 2008 Nov;34(11):1976-85. doi: 10.1016/j.jcrs.2008.07.029.
Posterior capsule opacification (PCO) remains the most common long-term complication after cataract surgery. Many studies have attempted to identify factors that influence the development of PCO. The aim of this systematic review based on Cochrane methodology was to summarize the effects of intraocular lens (IOL) geometry, including modifications of the IOL optic (especially optic edge design) and haptics, on the development of PCO. Twenty-six prospective randomized controlled trials with a follow-up of at least 12 months were included. In 5 of 7 studies, visual acuity was better in sharp-edged IOLs than in round-edged IOL. The PCO score was significantly lower with sharp-edged IOLs but did not differ significantly between 1-piece and 3-piece open-loop IOLs. Because of the significant difference in the PCO score, sharp-edged IOL optics should be preferred to round-edged IOL optics.
后囊膜混浊（PCO）仍然是白内障手术后最常见的长期并发症。许多研究试图确定影响PCO发生发展的因素。本基于Cochrane方法的系统评价旨在总结人工晶状体（IOL）几何形状，包括IOL光学部（尤其是光学边缘设计）和襻的改变，对PCO发生发展的影响。纳入了26项随访至少12个月的前瞻性随机对照试验。在7项研究中的5项中，锐边IOL的视力优于圆边IOL。锐边IOL的PCO评分显著更低，但单片式和三片式开环IOL之间无显著差异。由于PCO评分存在显著差异，锐边IOL光学部应优于圆边IOL光学部。
