使用钪催化剂将芳胺的苄基C-H加成到烯烃上。
Benzylic C-H addition of aromatic amines to alkenes using a scandium catalyst.
作者信息
Su Jianhong, Luo Yuncong, Xu Xin
机构信息
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, P. R. China.
出版信息
Chem Commun (Camb). 2021 Apr 18;57(30):3688-3691. doi: 10.1039/d1cc00306b. Epub 2021 Mar 16.
An efficient and selective benzylic C(sp)-H addition of o-CH-substituted tertiary aromatic amines to alkenes has been achieved using an anilido-oxazoline ligand supported scandium catalyst, which provides an atom-economic method for the synthesis of a new family of alkylated tertiary anilines. A wide range of amine and alkene substrates are compatible with the catalyst system.
使用一种苯胺基恶唑啉配体负载的钪催化剂，实现了邻碳氢键取代的叔芳胺与烯烃的高效、选择性苄基C(sp)-H加成反应，为合成一类新型烷基化叔苯胺提供了一种原子经济的方法。多种胺和烯烃底物与该催化体系兼容。
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