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DIY 人工胰腺:来自印度的首位患者和医生的经验叙事。

DIY artificial pancreas: A narrative of the first patient and the physicians' experiences from India.

机构信息

Jothydev's Diabetes Research Centre, Mudavanmugal, Thiruvananthapuram, Kerala, India.

DiaCare, Ahmedabad, Gujarat, India.

出版信息

Diabetes Metab Syndr. 2021 Mar-Apr;15(2):615-620. doi: 10.1016/j.dsx.2021.02.033. Epub 2021 Mar 10.

Abstract

BACKGROUND AIMS

Frustrated with the slow-pace of innovations in diabetes technologies, the type 1 diabetes community have started closing the loop by themselves to automate insulin delivery. While the regulatory and ethical concerns over the systems are still high, these have contributed to enhanced glycemic control characterized by improved estimated HbA1c and time-in-range above 90% as for many users. Our objective is to provide the real-world experience of the first successful patient from India on the Do-It-Yourself Artificial Pancreas (DIYAP) and the perspective of her physicians.

METHODS

A narrative recounting of a personal experience on DIYAP. The patient completed a Hypoglycemia Fear Survey II and Diabetes Quality of Life instrument before and after looping.

RESULTS

The patient emphasized the personal/social benefits and the concerns of using the system. Looping has produced a clinically meaningful difference in the quality of life, better sleep patterns, and reduced the disease management burden. We also highlighted the relevant perspectives of the physicians to give deeper insights into the aspect.

CONCLUSION

The patient highlighted better time-in-range, negligible time spent in hypoglycemia, and superior Quality of Life. Globally, more and more patients are adopting this technology; therefore, real-life patient stories will enlighten the medical community.

摘要

背景目的

由于对糖尿病技术创新的缓慢步伐感到沮丧,1 型糖尿病患者群体已开始自行闭环以实现胰岛素输送自动化。尽管这些系统的监管和伦理问题仍然存在,但它们有助于提高血糖控制水平,表现为许多用户的估计 HbA1c 和 90%以上时间的改善。我们的目的是提供印度第一位成功使用 DIYAP 的患者的真实体验以及她的医生的观点。

方法

个人 DIYAP 体验的叙述。患者在闭环前后完成了低血糖恐惧调查 II 和糖尿病生活质量量表。

结果

患者强调了使用该系统的个人/社交益处和担忧。闭环在生活质量、更好的睡眠模式和减少疾病管理负担方面产生了有临床意义的差异。我们还强调了医生的相关观点,以更深入地了解这一方面。

结论

患者强调了更好的时间范围内、低血糖时间显著减少和更高的生活质量。在全球范围内,越来越多的患者正在采用这项技术;因此,真实的患者故事将为医学界提供启示。

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