Suppr超能文献

无硬脑膜附着的脊髓内透明细胞型脑膜瘤:1例报告及文献复习

Intraspinal clear cell meningioma without dural attachment: A case report and literature review.

作者信息

Zhang Xiaolei, Zhang Peihai, Wang James Jin, Dong Sheng, Wu Youtu, Zhang Huifang, Wang Guihuai

机构信息

Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.

出版信息

Medicine (Baltimore). 2021 Mar 19;100(11):e25167. doi: 10.1097/MD.0000000000025167.

Abstract

RATIONALE

Clear cell meningioma (CCM) is one of the rarest but most aggressive forms of meningioma, with a tendency to occur at a high recurrence rate. Intraspinal CCM, especially the nondura-based type, is even rarer than the intracranial CCM.

PATIENT CONCERNS

We report a case of a 45-year-old woman who presented with a 1-month history of episodic pain in the lower back and in both thighs in the front side. Femoral nerve stretch tests were positive on both sides. Magnetic resonance imaging (MRI) demonstrated an intradural tumor at the L3 level, which was isointense on T1- and T2-weighted images (WI) and homogeneously enhanced on gadolinium-contrast T1 WI.

DIAGNOSES

The space-occupying lesion was pathologically confirmed as CCM.

INTERVENTIONS

During surgery, we found that the tumor adhered to a nerve root, without dural attachment. The nerve root was partially removed to achieve complete resection.

OUTCOMES

The pain disappeared after the operation. The 1 year follow-up MRI revealed no evidence of tumor recurrence or metastasis.

LESSONS

Nondura-based intraspinal CCM is easier to completely remove, and such complete removal should be achieved during the first operation. Although the recurrence rate of this particular type of meningioma appears to be lower than that of other types, close clinical and radiological follow-up is necessary.

摘要

理论依据

透明细胞型脑膜瘤(CCM)是脑膜瘤中最罕见但侵袭性最强的类型之一,具有高复发率的倾向。脊髓内CCM,尤其是非硬膜型,比颅内CCM更为罕见。

患者情况

我们报告一例45岁女性患者,有1个月下背部及双侧大腿前侧发作性疼痛病史。双侧股神经牵拉试验阳性。磁共振成像(MRI)显示L3水平硬膜内肿瘤,在T1加权像(WI)和T₂WI上呈等信号,钆对比剂增强T1WI上呈均匀强化。

诊断

占位性病变经病理证实为CCM。

干预措施

手术中,我们发现肿瘤与神经根粘连,无硬膜附着。部分切除神经根以实现完全切除。

结果

术后疼痛消失。1年随访MRI显示无肿瘤复发或转移迹象。

经验教训

非硬膜型脊髓内CCM更容易完全切除,应在首次手术时实现完全切除。尽管这种特殊类型的脑膜瘤复发率似乎低于其他类型,但仍需密切的临床和影像学随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2500/7982228/021ddecf8da4/medi-100-e25167-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验