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具有自适应色散校正的高分辨率多波长无透镜衍射成像。

High-resolution multi-wavelength lensless diffraction imaging with adaptive dispersion correction.

作者信息

Liu Yuanyuan, Liu Qingwen, Li You, Xu Bingxin, Zhang Junyong, He Zuyuan

出版信息

Opt Express. 2021 Mar 1;29(5):7197-7209. doi: 10.1364/OE.419128.

DOI:10.1364/OE.419128
PMID:33726225
Abstract

Multi-wavelength imaging diffraction system is a promising phase imaging technology due to its advantages of no mechanical movement and low complexity. In a multi-wavelength focused system, spectral bandwidth and dispersion correction are critical for high resolution reconstruction. Here, an optical setup for the multi-wavelength lensless diffraction imaging system with adaptive dispersion correction is proposed. Three beams with different wavelengths are adopted to illuminate the test object, and then the diffraction patterns are recorded by a image sensor. The chromatic correction is successfully realized by a robust refocusing technique. High-resolution images can be finally retrieved through phase retrieval algorithm. The effectiveness and reliability of our method is demonstrated in numerical simulation and experiments. The proposed method has the potential to be an alternative technology for quantitative biological imaging.

摘要

多波长成像衍射系统因其无机械运动和低复杂性的优点而成为一种很有前途的相位成像技术。在多波长聚焦系统中,光谱带宽和色散校正对于高分辨率重建至关重要。在此,提出了一种具有自适应色散校正的多波长无透镜衍射成像系统的光学装置。采用三束不同波长的光束照射测试物体,然后由图像传感器记录衍射图案。通过一种稳健的重新聚焦技术成功实现了色差校正。最终可以通过相位恢复算法检索到高分辨率图像。我们方法的有效性和可靠性在数值模拟和实验中得到了证明。所提出的方法有可能成为定量生物成像的替代技术。

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