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渐进性厚度角膜基质内环形片治疗鸭形圆锥角膜的疗效

Efficacy of progressive thickness intrastromal corneal ring segments in the treatment of duck phenotype keratoconus.

作者信息

Arbelaez Juan G, Arbelaez Maria C

机构信息

Muscat Eye Laser Center, Muscat, Shatti Al Qurum, Sultanate of Oman.

出版信息

Eur J Ophthalmol. 2021 Sep;31(5):2191-2199. doi: 10.1177/11206721211001722. Epub 2021 Mar 16.

Abstract

PURPOSE

To evaluate clinical outcomes in patients with asymmetric duck phenotype keratoconus implanted with asymmetric progressive thickness intrastromal corneal ring segments (PT-ICRS, Keraring AS, Mediphacos, Belo Horizonte, Brazil), and to demonstrate improved visual acuity and symmetry in corneal flattening.

METHODS

This single-center, retrospective, observational study evaluated the clinical outcomes at 1, 3, and 6 months after implantation of PT-ICRS in patients with duck phenotype keratoconus. After creating the intrastromal tunnel with a femtosecond laser, one 160-degree arc length PT-ICRS, either 150/250 µm or 200/300 µm, was implanted. Changes in uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction (MR), manifest refraction spherical equivalent (MRSE), mean keratometry (Kmean), maximum keratometry (Kmax), Coma@5mm, and manifest and topographical astigmatism were documented.

RESULTS

The study cohort included 23 eyes of 17 patients with a mean age of 24.6 years. From baseline to 6 months following implantation, mean UDVA improved from 0.70 logarithm of the minimum angle of resolution (logMAR) (20/100 Snellen) to 0.22 logMAR (20/33 Snellen), CDVA improved from 0.33 logMAR (20/42 Snellen) to 0.14 logMAR (20/27 Snellen), the mean sphere and MRSE decreased from -1.05 diopters (D) and -2.70 D to -0.25 D and -0.80 D, respectively, and the Kmean and Kmax improved from 46.5 D and 53.7 D to 44.6 D and 48.7 D, respectively.

CONCLUSIONS

The Keraring AS ICRS offers a safe, effective means of improving visual acuity while reducing refractive error, mean and max keratometry, and aberrations in patients with duck phenotype keratoconus.

摘要

目的

评估植入非对称渐进厚度角膜基质环段(PT-ICRS,Keraring AS,Mediphacos,巴西贝洛奥里藏特)的非对称鸭型圆锥角膜患者的临床结局,并证明视力改善和角膜变平的对称性。

方法

这项单中心、回顾性、观察性研究评估了鸭型圆锥角膜患者植入PT-ICRS后1、3和6个月的临床结局。用飞秒激光制作角膜基质隧道后,植入一个160度弧长的PT-ICRS,规格为150/250µm或200/300µm。记录未矫正远视力(UDVA)、矫正远视力(CDVA)、显验光(MR)、显验光球镜等效度(MRSE)、平均角膜曲率(Kmean)、最大角膜曲率(Kmax)、5mm处彗差以及显验光和地形图散光的变化。

结果

研究队列包括17例患者的23只眼,平均年龄24.6岁。从基线到植入后6个月,平均UDVA从最小分辨角对数(logMAR)0.70(20/100 Snellen)提高到0.22 logMAR(20/33 Snellen),CDVA从0.33 logMAR(20/42 Snellen)提高到0.14 logMAR(20/27 Snellen),平均球镜和MRSE分别从-1.05屈光度(D)和-2.70 D降至-0.25 D和-0.80 D,Kmean和Kmax分别从46.5 D和53.7 D提高到44.6 D和48.7 D。

结论

Keraring AS ICRS为改善鸭型圆锥角膜患者的视力提供了一种安全、有效的方法,同时可减少屈光不正、平均和最大角膜曲率以及像差。

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