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渐进性厚度角膜内环段植入术治疗鸭式圆锥角膜的临床、断层和拓扑学结果。

Clinical, tomographic, and topometric outcomes of progressive thickness intracorneal ring segment implantations in duck-type keratoconus.

机构信息

Department of Refractive Surgery, Dunyagoz Etiler Hospital; Faculty of Health Sciences, Istanbul Rumeli University, Istanbul, Turkey.

Department of Refractive Surgery, Dunyagoz Etiler Hospital; Department of Ophthalmology, Sultan II. Abdulhamid Han Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

出版信息

Indian J Ophthalmol. 2022 Aug;70(8):2939-2945. doi: 10.4103/ijo.IJO_2770_21.

Abstract

PURPOSE

To evaluate the visual, refractive, tomographic, and topometric outcomes of progressive thickness intracorneal ring segment (PT-ICRS) implantation in duck-type keratoconus.

METHODS

This retrospective study included eyes with oval (duck-type) keratoconus treated with PT-ICRS implantation. After the femtosecond laser tunnel creation, one PT-ICRS (Keraring AS 5 with 160° arc length) was implanted along the ectatic, inferior half of the cornea. Data of uncorrected and corrected distance visual acuity (UDVA and CDVA), refraction, asphericity (Q value), and keratometry (K) were compared pre- and postoperatively. Additionally, changes in the topometric indices of corneal irregularity were also evaluated after PT-ICRS implantation.

RESULTS

Thirty-one eyes of 30 patients were included in the study with a mean follow-up time of 9.06 months (ranging between 6 and 18 months). UDVA improved from 0.85 ± 0.36 to 0.27 ± 0.14 logMAR (P = 0.001), and CDVA improved from 0.37 ± 0.22 to 0.13 ± 0.11 logMAR (P = 0.001). The mean spherical error decreased from -3.66 ± 2.60 to -1.60 ± 1.42 D (P = 0.001), and the mean cylindrical error decreased from -4.91 ± 2.65 to - 1.41 ± 1.31 D (P = 0.001). All topographic parameters measured from the anterior cornea demonstrated statistically significant improvements after PT-ICRS implantation (P = 0.001). K mean, K maximum, corneal astigmatism, and Q value showed a significant decrease. Besides the index of height asymmetry, all topometric indices were significantly reduced after PT-ICRS implantation. There were no loss of lines and no complications.

CONCLUSION

PT-ICRS implantation in duck-type keratoconus is an effective and safe treatment. This intervention improves the visual acuity, refractive error, topographical, and topometric parameters significantly by decreasing both eccentricity and steepness of the cone.

摘要

目的

评估渐进式厚度角膜内环段(PT-ICRS)植入术治疗鸭跖状圆锥角膜的视力、屈光、断层和角膜地形学结果。

方法

本回顾性研究纳入了接受 PT-ICRS 植入术治疗的鸭跖状圆锥角膜眼。在飞秒激光隧道创建后,将一个 PT-ICRS(具有 160°弧长的 Keraring AS 5)植入沿扩张的、角膜的下侧。比较术前和术后未矫正和矫正的远距视力(UDVA 和 CDVA)、屈光、非球面性(Q 值)和角膜曲率(K)。此外,还评估了 PT-ICRS 植入术后角膜不规则性的拓扑指数变化。

结果

本研究纳入了 30 名患者的 31 只眼,平均随访时间为 9.06 个月(6 至 18 个月)。UDVA 从 0.85±0.36 提高到 0.27±0.14 logMAR(P=0.001),CDVA 从 0.37±0.22 提高到 0.13±0.11 logMAR(P=0.001)。平均球镜误差从-3.66±2.60 降低至-1.60±1.42 D(P=0.001),平均柱镜误差从-4.91±2.65 降低至-1.41±1.31 D(P=0.001)。PT-ICRS 植入术后所有前角膜测量的地形参数均有统计学意义的改善(P=0.001)。K 均值、K 最大值、角膜散光和 Q 值显著降低。除高度不对称指数外,PT-ICRS 植入术后所有拓扑指数均显著降低。没有线丢失和并发症。

结论

在鸭跖状圆锥角膜中,PT-ICRS 植入术是一种有效且安全的治疗方法。通过降低圆锥的偏心率和陡峭度,该干预措施显著改善了视力、屈光不正、地形和角膜地形学参数。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90de/9672792/9e3a0202665c/IJO-70-2939-g001.jpg

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