抗磷脂综合征导致反常栓子和通过房间隔缺损引发的脑卒中。
Antiphospholipid syndrome leading to paradoxical embolus and stroke via secundum atrial septal defect.
机构信息
Emergency Department, NHS Tayside, Dundee, UK.
Radiology, Ninewells Hospital and Medical School, Dundee, UK
出版信息
BMJ Case Rep. 2021 Mar 16;14(3):e239674. doi: 10.1136/bcr-2020-239674.
We have presented a case of a 22-year-old man, presenting with cerebral infarct, subsequently found to have antiphospholipid syndrome (APS), deep venous thrombosis, pulmonary embolism and atrial septal defect (ASD), thereby confirming the presence of infarct due to paradoxical embolism in this patient. The importance of ASD in the patients of APS, resulting in paradoxical embolism is debatable, with recent studies undermining its importance. We have demonstrated that it does indeed happen. This would have implications in the risk assessment and management of ASD in such patients. This case report is intended to serve as a reminder of this association and the need to perform further research in this area.
我们报告了一例 22 岁男性，以脑梗死为首发表现，后发现存在抗磷脂综合征（APS）、深静脉血栓形成、肺栓塞和房间隔缺损（ASD），从而证实该患者的梗死是由反常栓塞引起的。在 APS 患者中，ASD 导致反常栓塞的重要性存在争议，最近的研究削弱了其重要性。我们已经证明这种情况确实会发生。这将对这些患者的 ASD 风险评估和管理产生影响。本病例报告旨在提醒人们注意这种关联，并需要在该领域进行进一步研究。
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