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经皮注射富血小板血浆治疗尺骨骨折内固定术后萎缩性骨不连：病例报告。

Percutaneous injection of platelet-rich plasma to treat atrophic nonunion after internal fixation of ulnar fracture: a case report.

机构信息

The First Clinical College, Zhejiang Chinese Medical University, Hangzhou, China.

Department of Orthopaedics, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.

出版信息

Nagoya J Med Sci. 2021 Feb;83(1):201-208. doi: 10.18999/nagjms.83.1.201.

DOI:10.18999/nagjms.83.1.201
PMID:33727751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7938104/
Abstract

Non-union is a serious postoperative complication of fracture. Early detection and intervention can avoid revision surgery. Platelet-rich plasma releases many active tissue factors and has potential to promote fracture healing. Percutaneous injection of platelet-rich plasma at the fracture site may avoid surgical treatment when non-union occurs. We present a case of atrophic non-union of an ulna fracture treated conservatively with percutaneous injection of platelet-rich plasma.

摘要

骨折术后不愈合是一种严重的并发症。早期发现和干预可以避免进行翻修手术。富含血小板的血浆释放出许多活跃的组织因子，具有促进骨折愈合的潜力。当发生骨折不愈合时，经皮向骨折部位注射富含血小板的血浆可能可以避免手术治疗。我们报告了一例尺骨骨折萎缩性不愈合病例，采用经皮注射富含血小板的血浆进行保守治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/7938104/6bf07587b8df/2186-3326-83-0201-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/7938104/a5dfe7f6bc71/2186-3326-83-0201-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/7938104/ebfda3b1fdea/2186-3326-83-0201-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/7938104/6277f00a0d78/2186-3326-83-0201-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/7938104/a13ebb05676b/2186-3326-83-0201-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/7938104/5d3ae20d2005/2186-3326-83-0201-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/7938104/6bf07587b8df/2186-3326-83-0201-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/7938104/a5dfe7f6bc71/2186-3326-83-0201-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/7938104/ebfda3b1fdea/2186-3326-83-0201-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/7938104/6277f00a0d78/2186-3326-83-0201-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/7938104/a13ebb05676b/2186-3326-83-0201-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/7938104/5d3ae20d2005/2186-3326-83-0201-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b94e/7938104/6bf07587b8df/2186-3326-83-0201-g006.jpg

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本文引用的文献

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Curr Osteoporos Rep. 2018 Apr;16(2):155-168. doi: 10.1007/s11914-018-0432-1.
3
Diaphyseal long bone nonunions - types, aetiology, economics, and treatment recommendations.骨干长骨骨不连——类型、病因、经济学及治疗建议
Int Orthop. 2018 Feb;42(2):247-258. doi: 10.1007/s00264-017-3734-5. Epub 2017 Dec 22.
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Role of isolated percutaneous autologous platelet concentrate in delayed union of long bones.孤立的经皮自体血小板浓缩物在长骨延迟愈合中的作用。
Eur J Orthop Surg Traumatol. 2018 Jul;28(5):985-990. doi: 10.1007/s00590-017-2077-7. Epub 2017 Nov 22.
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Nonunion of Fractures of the Ulna and Radius Diaphyses: Clinical and Radiological Results of Surgical Treatment.尺桡骨干骨折不愈合：手术治疗的临床及影像学结果
Malays Orthop J. 2016 Jul;10(2):27-34. doi: 10.5704/MOJ.1607.006.
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Fracture healing physiology and the quest for therapies for delayed healing and nonunion.骨折愈合生理学以及对延迟愈合和骨不连治疗方法的探索。
J Orthop Res. 2017 Feb;35(2):213-223. doi: 10.1002/jor.23460. Epub 2016 Dec 19.
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The biomechanical and histological effects of platelet-rich plasma on fracture healing.富血小板血浆对骨折愈合的生物力学及组织学影响。
Knee Surg Sports Traumatol Arthrosc. 2015 May;23(5):1378-1383. doi: 10.1007/s00167-013-2734-2. Epub 2013 Oct 30.
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